article
23 October 2024 | By Dr Jorg Scheuermann (ETH Zurich), Dr Michelle Keller (ETH Zurich)
So-called undruggable pharmaceutical targets could be tackled with intermediate sized drugs such as macrocycles, combining the advantages of small molecules and biologics. The preparation of very large libraries of chemically synthesised intermediate-sized molecules is now in reach with a new technology developed at ETH Zurich. In this article, Dr Michelle…