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Inflammation discovery offers hope for age-related diseases
Researchers have made a significant breakthrough in the field of ageing research, uncovering a key driver of chronic inflammation that accelerates the ageing process.
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Fraser Owen (Drug Target Review)
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Game-changing pan-TEAD inhibitor for solid tumours
Insilico Medicine has announced the nomination of ISM6331 as a potential best-in-class pan-TEAD inhibitor for the treatment of advanced solid tumours.
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Understanding molecular mechanisms behind breast cancer
Oestrogen receptors play a crucial role in breast cancer. By making them therapeutic targets, oestrogen can be regulated with the aim to prevent breast cancer.
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Transforming the way cancer vaccines are designed and made
Researchers found that ‘rational vaccinology’ increases potency by changing the structural location of antigens and adjuvants.
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Specific gene implicated in cardiovascular calcification
Researchers have found a gene that is crucial for the calcification of cardiovascular vessels in mice, which could be a target for heart attacks and stroke.
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New CRISPR technique could alter the way we look at brain diseases
Researchers may have fundamentally altered the way scientists study brain diseases with new CRISPR technology.
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Process for rejuvenating aged rat brain stem cells discovered
A research team has developed a method for regenerating old brain stem cells from rat models, which could be used to treat age-related brain diseases.
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Macrophages identified as cause of endometriotic pain
Researchers have discovered that macrophages are a key cause for pain in women with endometriosis so could be a treatment target for the condition.
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New technique developed to expand multimodal single cell analysis
A new technique, called ECCITE-seq, has been developed to allow researchers to perform high-throughput measurements of multiple modalities of information from single cells.
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Cancer vaccine shows promising results in Lynch syndrome
Vaccination with as few as four tumour antigens generated antigen-specific responses, reduced intestinal tumours, and improved survival in a mouse model of Lynch syndrome...
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Protein marker in response to brain cancer therapy
An extremely powerful MRI scanner was used to image proteins in the brain of cancer patients and has shown that protein content correlates with treatment...
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Digital 3D brain cell atlas released
The Blue Brain 3D atlas could be the future of analysing all cells in the brain, with high quality, high resolution images that can navigate the brain...