Gabriele Sorg (Hit Discovery Constance)

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Assays In-Depth Focus 2016

17 March 2016 | By David Shum (Institut Pasteur Korea), Gabriele Sorg (Hit Discovery Constance), Horst Flotow

In this Assays In-Depth Focus: "Finding a cure for neglected tropical diseases with cell-based assays", plus "The relevance of homogeneous radiometric assays in modern drug discovery"...

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The relevance of homogeneous radiometric assays in modern drug discovery

14 February 2016 | By Gabriele Sorg (Hit Discovery Constance), Horst Flotow (Singapore Screening Centre)

In the past two decades, several alternative, non-radiometric assay formats have been developed for the high-throughput screening (HTS) of target classes such as protein kinases, which were previously screened using radiometric assays. Radiometric screening (and the expertise to perform such HTS) has thus declined in recent years...