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Guide: Screening biologic candidates with nanoDSF
Read this guide about nanoDSF for high-resolution measurements of thermal stability parameters, common CQAs for biologics developability assessment.
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NanoTemper Technologies
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Infographic: Biologics stability in early development
Stability attributes of biologic candidates are evaluated during early development workflows. Learn how to measure them with biophysical techniques.
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Video: Four integrated technologies for biologics developability assessment
The decisions you make about your biologics candidates early in the pipeline ultimately affect their success as therapeutics. Combine sizing and stability information to develop successful biologics.
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Brochure: Overcome roadblocks in your PROTAC characterizations with Dianthus
Learn how Dianthus resolves common challenges you face during the characterization of PROTAC binary and ternary complexes and the determination of cooperativity.
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Infographic: Targeted protein degradation
In this infographic, we discuss both inhibition and degradation, the advantages and challenges related to each approach and the key points you need to consider when designing your protein degraders.
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Guide: How to build an effective protein degrader
This guide highlights the four major stages of TPD, the challenges at each step and questions you should ask yourself.
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ebook: The biologics researcher’s guide to dynamic light scattering
Learn about DLS, a powerful method to characterise the purity and aggregation state of your biologics for improved candidate selection.
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NanoTemper Technologies launches Spectral Shift, a breakthrough technology that changes the game for affinity-based screenings
NanoTemper Technologies has announced the launch of Spectral Shift technology with its Dianthus instrument.
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ebook: The researcher’s guide to measuring binding affinity
Learn why measuring binding affinity is key to helping you decide the next steps in your research and what technologies are available to measure it.
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ebook: The definitive guide to understanding protein stability
Learn how to measure protein stability, why it’s important, and what the key technologies are available to measure it.
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ebook: How FBDD improves hit rates & delivers high-value targets
Learn how fragment-based drug discovery improves hit rates and delivers higher-value targets using various biophysical methods.
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Guide: Five ways biophysical tools help brain studies
Learn why researchers turned to biophysical methods to expose the molecular mechanisms of neurodegenerative diseases.
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ebook: How to start your own lab
Learn practical tips from eight Principal Investigators about how to start your own lab.
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Application note: Faster and more reliable quantification of oligonucleotide interaction with human serum albumin using MST
Antisense oligonucleotides are an emerging therapeutic option for treating diseases with known genetic origin.
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Fast molecular interaction screening for all your projects
Current technologies that measure molecular interactions for drug discovery slow down and complicate screening. Dianthus is the answer to the demands for fast, non-stop, highly sensitive hit identification, hit validation and lead optimisation.