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30 November 2018 | By Maria Kuzikov (Fraunhofer-IME SP), Oliver Keminer (Fraunhofer Institute for Molecular Biology and Applied Ecology), Salma Hachim (Fraunhofer Institute for Molecular Biology and Applied Ecology), Sheraz Gul (Fraunhofer-IME SP)
Many drugs fail in clinical trials due to toxicity-related issues; therefore, drug-mediated cellular toxicity should be determined at an early stage in the drug discovery value chain. There are many assay systems that can be utilised to measure cellular toxicity. In this article we demonstrate that intracellular ATP concentrations are…
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