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Cancer research

news

Blood test developed that reliably detects NEPC

11 January 2024 | By Drug Target Review

A new blood panel test reports the tumour fraction and the tumour type of prostate cancer with a high level of accuracy.

news

CBPUV nanoparticles show excellent anticancer activity

10 January 2024 | By Drug Target Review

Novel self-assembled amino acid-based nanoparticles, loaded with doxorubicin, could evolve cancer treatment.

whitepaper

eBook: Modern Microscopy in Cancer Research

10 January 2024 | By Leica Microsystems

Explore the history and trends of microscopy in cancer research and discover the latest cancer imaging solutions and techniques in this eBook.

news

Advancing the development of CTLA-4 inhibitors

8 January 2024 | By Drug Target Review

A new study could result in CTLA-4 inhibitors that promote antitumour responses without causing intestinal diseases, such as colitis.

news

Controlling MYC’s hyperactivity with a peptide compound

8 January 2024 | By Drug Target Review

A novel peptide can suppress MYC by binding directly to it with sub-micro-molar affinity, advancing cancer drug development.

article

Allosteric control sites in KRAS protein found

5 January 2024 | By Ellen Capon (Drug Target Review)

The first complete control map for any protein has been made for KRAS, and four potential drug targets have been discovered.

news

Targets for pancreatic cancer treatment found

2 January 2024 | By Drug Target Review

Using tumour organoids, researchers have found a starting point for the development of a more refined PDAC drug.

article

Not all neoantigens are created equal

28 December 2023 | By Dr Sergio Quezada (Achilles Therapeutics)

Founder and CSO of Achilles Therapeutics Dr Sergio Quezada reveals how the landmark TRACERx study has gleaned key insights that could make the difference between success and failure in immunotherapy treatment.

article

Drug Target Review – Issue 4 2023

21 December 2023 | By

A new Drug Target Review issue is now ready to download! This issue features articles on CRISPR, personalised medicine and screening.

article

New understanding of the TMEJ pathway in cancer

14 December 2023 | By Ellen Capon (Drug Target Review)

Cancer treatment may be majorly impacted by new findings about the polymerase theta-mediated end joining time DNA repair pathway.

MRI of a glioblastoma in the brain of a patient (in frontal lobe near the right eye)

news

Perivascular fibroblasts support glioblastoma tumours

13 December 2023 | By Drug Target Review

Glioblastomas can resist immunotherapy as perivascular fibroblasts support the creation of an immunosuppressive tumour environment.

news

New organoid model of neuroendocrine tumours developed

13 December 2023 | By Drug Target Review

NETs require epidermal growth factor to grow, meaning that inhibiting EGF receptors could treat these types of tumours.

whitepaper

eBook: A Microscopy Guide For Spatial Biology

11 December 2023 | By Leica Microsystems

In this eBook, discover how to better understand tissue landscapes with different microscopy techniques including multiplex imaging.

news

Gene therapy reduces hepatocellular carcinoma in mice

8 December 2023 | By Drug Target Review

Increasing microRNA-22 overexpression in a gene therapy approach treated HCC in mice, offering promise for its prevention and treatment.

whitepaper

Beyond the lab: cancer research

6 December 2023 | By Drug Target Review

Our inaugural report is an exploration of the remarkable advancements in cancer research and the field of drug discovery.

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Cancer research