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Cell & gene therapy

Understanding how macrophages direct tissue regeneration

5 February 2024 | By Ellen Capon (Drug Target Review)

Distinct macrophage signatures that align specifically with regeneration could offer novel therapies to enhance wound healing.

news

Off-switches developed for CRISPR-Cas3 technologies

22 January 2024 | By Drug Target Review

AcrlC8 and AcrlC9 prevent the CRISPR-Cas3 machine from binding to its DNA target site, providing a safer way to engineer the genome.

news

Discovery of a previously unknown class of HK-CREs

9 January 2024 | By Drug Target Review

Using bioinformatics analyses, HK-CREs impact on cellular processes was studied, including their potential as housekeeping tumour suppressors.

whitepaper

Article: Tips and Tricks for Leveraging Advanced Flow Cytometry

9 January 2024 | By Sartorius iQue®

Tips and tricks for fully leveraging Advanced Flow Cytometry.

news

New technology to effectively regulate gene expression

3 January 2024 | By Drug Target Review

A new strategy enables researchers to be more precise in the control of gene expression of a therapeutic protein.

article

Drug Target Review – Issue 4 2023

21 December 2023 | By

A new Drug Target Review issue is now ready to download! This issue features articles on CRISPR, personalised medicine and screening.

news

Gene therapy reduces hepatocellular carcinoma in mice

8 December 2023 | By Drug Target Review

Increasing microRNA-22 overexpression in a gene therapy approach treated HCC in mice, offering promise for its prevention and treatment.

news

An altered protein can combat the growth of leukaemia cells

6 December 2023 | By Drug Target Review

Discovery about the NPM1c variant could lead to new drugs targeting the cell growth of acute myeloid leukaemia.

whitepaper

Beyond the lab: RNA

6 December 2023 | By Drug Target Review

Download this exclusive content focusing on new RNA editing technology, the challenges and opportunities presented and the potential of RNA-based therapeutics.

news

The IKAROS protein is crucial for B cell development

5 December 2023 | By Drug Target Review

By mapping the genome, scientists have discovered how IKAROS enables differentiation of hematopoietic stem cells into B cells.

article

New technology optimises mesenchymal stem cell extraction

1 December 2023 | By Ellen Capon (Drug Target Review)

A continuous sorting technique of stem cells on a DLD microfluidic platform may greatly advance cell therapy.

news

New contamination-detection test to improve T-cell therapy

28 November 2023 | By Drug Target Review

Method to improve sterility assurance in biopharmaceutic manufacturing will lead to better patient outcomes.

news

Noncoding RNA could be a new target for acute myeloid leukaemia

23 November 2023 | By Drug Target Review

Discovery about the DNA of leukaemia cells suggests promising target for gene therapy in paediatric oncology.

news

Genetically engineered transplants avoid immune rejection

23 November 2023 | By Drug Target Review

Researchers have found a way to genetically modify stem cells so that cell and organ transplants are not rejected.

news

Promising strategy for glaucoma cell replacement therapy

20 November 2023 | By Drug Target Review

Changing blood stem cells into retinal ganglion cells that can migrate to the eye’s retina offers hope for cell replacement therapy.

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Cell & gene therapy