article
Unlocking the power of machine learning for small molecule drug discovery
Rick Wagner of ZebiAI and Patrick Riley of Google Accelerated Science (GAS) discuss the development and benefits of a new machine learning drug discovery platform.
List view / Grid view
Hit-to-Lead
news
Four compounds discovered in starfish show efficacy against cancer cells
Scientists have revealed that four molecules found in the Ceramaster patagonicus starfish show potency against cancer in cell lines.
webinar
Drug repurposing approaches to fast track development of new therapies for COVID-19
26 June 2020 | By Tecan
This webinar described the recent efforts to identify small molecule therapeutics for the treatment of SARS-CoV-2 infection and COVID-19 disease.
news
Promising COVID-19 drug candidate identified by virtual screening
After virtually screening 640 existing drug compounds, researchers have revealed that PC786 potently targets several SARS-CoV-2 receptors, making it a candidate to fight COVID-19.
news
Over 718 drugs in pipeline as potential COVID-19 treatments, says report
New research has found that of the 718 pipeline drugs associated with COVID-19, 70 percent are currently in the discovery or pre-clinical stages.
news
Novel compound could treat type 2 diabetes without common side effects
Two molecules combined into a new substance to treat type 2 diabetes lowered blood sugar in shrew models without causing nausea, vomiting and weight loss.
whitepaper
ebook: The researcher’s guide to measuring binding affinity
Learn why measuring binding affinity is key to helping you decide the next steps in your research and what technologies are available to measure it.
news
Screening reveals nelfinavir and amodiaquine combat COVID-19 in cell cultures
Researchers who screened 136 broad-spectrum antivirals identified six with the most activity against COVID-19 and an optimum combination of two to fight the virus.
whitepaper
ebook: The definitive guide to understanding protein stability
Learn how to measure protein stability, why it’s important, and what the key technologies are available to measure it.
webinar
Improving cell-based assays and their future in drug discovery
15 June 2020 | By Horizon Discovery
Watch our on-demand webinar with Horizon Discovery which summarises the challenges in translating promising pre-clinical therapeutic candidates into clinical success.
news
Naphthalene-based PLpro inhibitors show potential as COVID-19 therapeutics
A group of small molecules called naphthalene-based PLpro inhibitors have been shown to block the activity of a SARS-CoV-2 protein, demonstrating potential as COVID-19 therapeutics.
video
Video: ESHG 2019 conference discussion panel: automated sample preparation
A result is only as good as the sample preparation that preceded it.
video
Video: Overview of the KingFisherTM instruments
ESHG 2019: Automated sample preparation using magnetic bead technology and KingFisher instruments.
video
Video: Isolate Circulating tumor cells using the KingFisher
New opportunities for liquid biopsy: At automated workflow for isolating circulating tumor cells using KingFisher instruments.
whitepaper
ebook: How FBDD improves hit rates & delivers high-value targets
Learn how fragment-based drug discovery improves hit rates and delivers higher-value targets using various biophysical methods.