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Breast cancer progression may be halted with CRISPR gene editing

26 August 2019 | By Rachael Harper (Drug Target Review)

A tumour-targeted CRISPR gene editing system encapsulated in a nanogel could halt the growth of triple-negative breast cancer.

news

Researchers image structure of cancer metastasis target

22 August 2019 | By Victoria Rees (Drug Target Review)

The structure of a key receptor involved in tumour metastasis has been imaged in a study, providing opportunities to develop cancer treatments.

news

Cyclisation reaction enables screening of macrocyclic compounds libraries

22 August 2019 | By Rachael Harper (Drug Target Review)

Libraries of more than 9,000 macrocyclic molecules below 1 KDa have been generated, small enough to cross cell membranes and reach targets.

news

Osteoporosis in mice reversed with new drug target

21 August 2019 | By Rachael Harper (Drug Target Review)

A pharmaceutical target has been identified by Duke University that, when activated, can reverse bone degradation caused by osteoporosis.

news

Optofluidic chip platform developed for single molecule analysis

19 August 2019 | By Rachael Harper (Drug Target Review)

A new platform has enabled an unprecedented level of control over individual molecules and particles on a chip for high-throughput analysis.

article

Applying AI language translation to the creation of new pharmaceuticals

16 August 2019 | By Dr Sam Genway

Designing new drug molecules is crucial to R&D. Dr Sam Genway suggests that one way to improve and speed up this process is using AI inspired by language translation.

news

Anti-viral immune discovery could lead to improved vaccines

14 August 2019 | By Rachael Harper (Drug Target Review)

A molecular switch that impacts immune responses to viral infections has been identified which could lead to better strategies to develop vaccines.

news

Molecular Devices introduces the FLIPR^® Penta system

2 August 2019 | By Molecular Devices

Molecular Devices, LLC, today announced the launch of the next generation of its FLIPR® Penta High-Throughput Cellular Screening System.

news

New discovery could lead to new treatments for Parkinson’s

30 July 2019 | By Drug Target Review

New discovery makes it possible to design new therapies to replace alpha-synuclein's function in people with Parkinson's disease.

news

Study shows p38 protein regulates formation of new blood vessels

18 July 2019 | By Drug Target Review

A new study shows that the activity of p38 is important in MSCs, which can localise around blood vessels.

news

Gene differences that impact response to Cryptococcus identified

17 July 2019 | By Drug Target Review

Using human data, a new study has examined how Cryptococcus genes impact patients with Cryptococcus Neoformans.

news

Chemical synthesis and biological screening combined on chip

16 July 2019 | By Victoria Rees (Drug Target Review)

Researchers have developed a chip which facilitates and accelerates active substance production, characterisation and biological effectiveness.

news

Light-stimulated brain cells could aid in stroke recovery research

1 July 2019 | By Drug Target Review

A new 'optochemogenetics' research approach from scientists at the Emory University School of Medicine could aid in helping stroke victims.

news

Job cuts limit cardiovascular and diabetes research and development

25 June 2019 | By Drug Target Review

Pharmaceutical company, Sanofi, will eliminate jobs in France and Germany and end new in-house cardiology research programmes.

news

Scientists have discovered important redundancies in T cells

21 June 2019 | By Drug Target Review

Redundancies have been discovered in the biochemical signalling pathways of immune cells which could impact cancer immunotherapy.

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