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Light-based production of drug discovery molecules
Researchers have developed a method of using photocathodes and photoanodes to catalyse reactions that turn organic molecules into drug discovery ones...
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Reversible antiplatelet therapy fights cancer metastasis and clotting
A novel antiplatelet therapy could help to prevent heart attacks and stroke through preventing the formation of blood clots...
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Protection against Mayaro virus using engineered DNA vaccine
An engineered DNA vaccine that induces a robust and specific immune response against the disease, also provides complete protection...
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Hit-to-lead discovery at a nonprofit research institute
Small molecule drug discovery has long been the domain of pharmaceutical companies, and that’s not likely to change anytime soon. But there’s a cadre of universities and nonprofit research institutes that have embraced drug development at its earliest stages, in some cases identifying and optimising compounds that target possible disease-driving…
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Virtual drug discovery tackles unknown universe of drugs
An online compound library consisting of the structure of over a billion molecules could be the future of drug discovery...
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The path of metallodrugs in breast cancer cells
The path a metallodrug uses to target and kill cancer cells could be used to design drugs to target triple-negative breast cancer...
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Drug compound could be next-generation treatment for aggressive form of AML
Researchers have developed a series of compounds that work not only on AML with common FLT3 mutation but also drug-resistant AML...
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Chicken eggs containing human proteins could be key for future therapies
Hens that lay human proteins in their eggs could offer hope for future therapies, especially with the simple, cost-effective system used...
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Mavoglurant could improve eye gaze in fragile X patients
A first stage trial involving the experimental drug mavoglurant has shown early success in the treatment of gaze avoidance in fragile X syndrome patients...
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‘Hidden pocket’ could be targeted to treat strokes
Researchers have identified a tiny hidden pocket on the NMDA receptor that could be targeted to treat strokes and seizures...
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Nuclear tracers help assess new drugs for neurodegenerative diseases
New nuclear medicine tracers could help medical researchers find a cure for Alzheimer's and other neurodegenerative diseases.
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Naturally occurring potent antibiotic revealed
A natural antibiotic was found to be made from an enzyme, through it triggering chemical reactions that help the production of the bacterial toxin...
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Producing vaccines without the use of chemicals
Innovative new technology will use electron beams to produce inactivated vaccines quickly, reproducibly and without the use of chemicals...
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Small molecules could have big benefits in the battle against cancers
Immunotherapy and targeted treatments, including targeted chemotherapy, continue to show great potential in cancer care. Future steps in their development will involve improving their ability to treat a wider range of cancers and a broader cross-section of the patient population, especially those for whom current treatments have shown limited efficacy...
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Inhalable mRNA could treat lung disease
An inhalable mix of a polymer and mRNA molecules, used to produce luciferase, could be the method of treating lung diseases in the future...