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Researchers uncover the role of PAD4 in cancers
8 February 2016 | By Victoria White
Peptidyl arginine deiminase 4 (PAD4) is a protein that plays a role in the development of inflammatory diseases like arthritis...
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Inhibiting cell death may prevent the spread of cancer
5 February 2016 | By Victoria White
New research suggests that drugs to prevent, rather than encourage, cell death might be effective at fighting cancer - contrary to how many of the current chemotherapy drugs work...
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Mersana and Takeda expand partnership to advance XMT-1522
3 February 2016 | By Victoria White
XMT-1522 is an investigational, Fleximer-based ADC therapy that targets HER2-expressing tumours, including breast, gastric and non-small cell lung cancers...
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London Cancer Hub to accelerate the discovery of treatments
3 February 2016 | By Victoria White
A new ‘roadmap’ document published today outlines how The London Cancer Hub will become a world-leading life-science campus...
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Adaptimmune and GSK expand cancer immunotherapy collaboration
3 February 2016 | By Victoria White
The enhanced agreement will accelerate Adaptimmune’s lead clinical cancer programme, an affinity enhanced T-cell immunotherapy targeting NY-ESO-1...
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MISSION Therapeutics raises £60m to advance DUB inhibitors
2 February 2016 | By Victoria White
The £60 million enables the company to maximise the potential of its DUB platform and advance a series of DUB inhibitors...
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Epigenome mining leads to medulloblastoma discovery
29 January 2016 | By Victoria White
Researchers have identified the cells that likely give rise to the brain tumour subtype Group 4 medulloblastoma, removing a barrier to developing more effective targeted therapies....
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ADC Summit 2016 to highlight the developments for next wave of antibody-drug conjugates
29 January 2016 | By SMi Group
Registration now live for the 5th annual ADC Summit taking place at the Holiday Inn Kensington Forum, London, UK on the 23rd – 24th May 2016...
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Karolinska Institutet and Biovica to evaluate promising cancer treatments
29 January 2016 | By Victoria White
The lab headed by Thomas Helleday at Karolinska Institutet and Biovica are to collaborate to improve evaluation of new, promising cancer therapies...
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Drug Target Review’s top 10 stories from 2015
28 January 2016 | By Victoria White, Digital Content Producer, Drug Target Review
2015 was an exciting year for the drug discovery industry. Here we look at a selection of stories that particularly stood out for us…
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ADDoPT project set to transform the UK pharma industry
28 January 2016 | By Victoria White
The ADDoPT project addresses the key challenge of getting new innovative medicines to market in the quickest and most cost-effective way...
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Myeloma UK and the SGC in first-of-its-kind collaboration
27 January 2016 | By Victoria White
Myeloma UK and the SGC have entered into an open-access research partnership to discover drug targets for myeloma using structural biology and chemical proteomics...
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Nanoparticles inhibit liver cancer tumour growth in study
26 January 2016 | By Victoria White
Scientists from UTSW have crafted synthetic "dendrimer" nanoparticles that are able to provide a tumour-suppressing effect without further damaging the liver or neighbouring tissue...
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Laser cut microwells could lower the cost of cancer research
26 January 2016 | By Victoria White
Researchers say the fabrication technique could slash 90% of the cost of mass-producing metastatic microtumours and therapeutic microtissues for screening and research...
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New mechanism of anti-tumour action identified in ABTL0812 study
26 January 2016 | By Victoria White
During trials of ABTL0812, researchers identified a new mechanism of action: the activation of the PPAR receptors and the TRIB3 gene, leading to inhibition of the Akt/mTOR pathway...
