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ebook: Get a front row view of your cells
Discover how you can simplify your workflow by combining microplate reading and imaging in a small footprint.
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Imaging
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Researchers capture images of cells infected with SARS-CoV-2
Using scanning electron microscopy, researchers have captured images of epithelial cell cultures infected by SARS-CoV-2.
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Researchers visualise how orthoreovirus assembles inside infected cells
Researchers have captured the assembly of orthoreovirus, part of the Reoviridae family, inside infected cells using cryo-electron tomography.
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Drug Target Review – Issue 3 2020
This issue includes articles that explore how a next-generation genomics platform can be used for COVID-19 research, the elimination of neutralising AAV antibodies for gene therapies and a new quick and cost-effective biomarker technology for cancer diagnostics. Also in this issue are features on antibody therapeutics for COVID-19 and targets…
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Inhibiting growth factor signalling prevents SARS-CoV-2 replication, report researchers
Scientists have patented their technique of inhibiting cellular growth factor signalling to stop SARS-CoV-2 replication and treat COVID-19.
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Novel alpha-synuclein structures could be the target for future Parkinson’s therapies
Researchers observed new structures of alpha-synuclein aggregates in their study exploring how the presence of cell membrane phospholipids impacts protein aggregation.
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Researchers observe interaction between antibodies and target proteins
Using cryogenic electron microscopy, scientists have observed the interaction between antibodies and their target molecules, providing information that could be utilised in the development of synthetic antibodies.
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Webinar: HCP assays to improve risk mitigation
HCPs are critical to quality control in biologics development. If left unremoved, they can cause immunogenic responses and reduce drug efficacy.
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Technique to visualise hundreds of genomes simultaneously developed
A new technology named OligoFISSEQ has been created which can image and three-dimensionally map the genomes in hundreds of cells at the same time.
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Five of the most recent microscopy developments
Drug Target Review highlights five of the latest imaging advancements in the field of microscopy.
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Could the Nsp1 protein be a novel drug target for COVID-19?
A study of the SARS-CoV-2 nonstructural protein 1 (Nsp1) showed it can supress translation and inhibit anti-viral defence mechanisms, making it a potential target for drugs.
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Interview: Stefan Braam, CEO & Founder of Ncardia
Mass production with iPSCs: how Ncardia has pushed the boundaries with high-throughput iPSC research.
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Whitepaper: Neuroinflammation study
Neuroinflammation study by combining human iPSC-derived astrocytes and HTRF.
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Brochure: Particle analysis re-imagined with the Aura™
Get reproducible and quantitative count, size, morphology and particle ID in one system with the Aura™.
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Whitepaper: iPSC manufacturing for drug discovery
Controlled manufacturing of hiPSC-derived cardiomyocytes in stirred-tank bioreactors enabling high-throughput phenotypic screening.