Imaging

Application note: In Vivo Imaging with GFP

12 November 2019 | By Analytik Jena

Challenge: Non-invasive imaging of a patient-derived orthotropic mouse model of pancreatic cancer expressing GFP. The solution? In vivo imaging.

eBook – Getting the Inside Story: In Vivo Imaging

12 November 2019 | By Analytik Jena

In vivo imaging has been an indispensable and powerful tool in biomedical research, enabling a number of significant breakthrough discoveries.

Analytik Jena

Application note: Analysis of Inflammatory Plasma Biomarkers in Cancer Patient Samples

6 November 2019 | By Quanterix

The Simoa CorPlex Human Cytokine Panel 1 is a multiplex immunoassay for the quantitative measurement of 10 inflammatory biomarkers in serum and EDTA plasma.

First detailed 3D image of astrocytes produced by researchers

30 October 2019 | By Victoria Rees (Drug Target Review)

Researchers have compiled images to create the first detailed 3D models of astrocytes, which could be used in the development of therapeutics to aid their function.

Clues discovered for why MYH9 gene mutations cause human disorders

29 October 2019 | By Rachael Harper (Drug Target Review)

A new study has demonstrated for the first time that mutations that affect myosin motor activity result in slower cell movements in vivo.

Application note: Assess cell viability and proliferation with colorimetric readouts

29 October 2019 | By Molecular Devices

MTT and Cell Cytotoxicity assay kits from Abcam can both be used to measure cell proliferation (viable cells) and cytotoxicity. The choice of which assay to use is mainly based on the desired workflow and time required to complete an assay.

Researchers reveal how body repairs damaged DNA

28 October 2019 | By Victoria Rees (Drug Target Review)

A team has imaged the process that the body uses to stabilise DNA, which could be used to develop therapies for conditions such as cancer.

Rhomboid protease role observed using dynamic imaging

28 October 2019 | By Rachael Harper (Drug Target Review)

Researchers have been able to watch rhomboid proteases in a native lipid environment which may be useful for the development of Parkinson's and malaria medication. 

Application note: Streamline BCA-based protein quantitation on the SpectraMax iD5 reader

23 October 2019 | By Molecular Devices

Learn how to quantitate a cellular protein sample with BCA protein assay kits on the SpectraMax® iD5 Multi-Mode Microplate Reader from Molecular Devices.

Collaborative enzyme study could lead to a target for cancer therapeutics

21 October 2019 | By Rachael Harper (Drug Target Review)

A new study into the enzyme Cdc34 may make it possible to target the enzyme specifically to develop new cancer therapeutics.

ImageXpress Pico Automated Cell Imaging System – Interactive Demo

21 October 2019 | By Molecular Devices

The ImageXpress® Pico Automated Cell Imaging System from Molecular Devices is more than a digital microscope, combining high-resolution imaging with powerful analysis.

Application note: Evaluate anti-inflammatory compounds using a multiparametric THP-1 cell-based assay

18 October 2019 | By Molecular Devices

Macrophages originate from blood monocytes that leave the circulation and penetrate various tissues where they differentiate into macrophages. They are involved in the removal of pathogens and phagocytosis of dead cells. In addition, they initiate inflammation by releasing cytokines that activate vascular cells and facilitate macrophage adhesion to blood vessels…

New technology invented to streamline drug discovery

8 October 2019 | By Rachael Harper (Drug Target Review)

New protein-painting technology could lead to developing cancer immunotherapy medicines that can be administered as a pill. 

Video: SpectraMax i3x Multi-Mode Microplate Reader

4 October 2019 | By Molecular Devices

An unlimited breadth of user-upgradeable application modules expands your research capabilities and evolves with your research