news
Open-source framework developed for automated pipetting and imaging
Scientists have demonstrated how automated, high-throughput life science experiments can be replicated on a modest budget.
List view / Grid view
Imaging
news
Breakthrough method developed to grow model organs
Researchers have successfully generated organoids in suspension, offering the possibility of larger-scale experiments to study human development and disease.
webinar
Image-based, quantitative approaches to study SARS-CoV-2 cell entry and infection: looking for the Achilles’ heel of virus infection
21 February 2022 | By Yokogawa Deutschland GmbH
Watch our free on-demand webinar to discover how fully automated imaging and image analysis can provide the unprecedented possibility to follow single viral particles, including for SARS-CoV-2.
news
New cryo-EM method reveals insight into blood disorders
A molecular cage, developed for use during cryo-EM, has provided researchers with new insights into a key cancer protein.
news
New research sheds light on what influences target protein binding time
The length of time that drug molecules attach to their target protein varies greatly and impacts the protein’s behaviour and drug efficacy. In a new study, scientists in Finland have identified some causal factors for this variance, with the hope it will bring clarity for drug developers.
news
Scientists unveil first molecular-level analysis of Omicron spike protein
Using cryo-electron microscopy, researchers have completed the world’s first molecular analysis of the SARS-CoV-2 Omicron spike protein.
news
Model insight into blood enzyme Lp-PLA2 could aid cardiovascular health
A new study in the US has used a computer model to reveal the mechanism of action of lipoprotein-associated phospholipase A2 – a biomarker for cardiovascular disease.
article
T-cell immunotherapies and flow cytometry
Dr Alasdair Gunn and Natalie Bath from Adaptimmune explain how flow cytometry provides a useful tool for the development of immuno-oncology therapies. They also explore how they use this method for translational research of the company’s SPEAR T-cell products.
article
Flow cytometry in drug discovery and development
With a range of tools available to scientists in the field of therapeutic discovery and development, flow cytometry presents an advantageous method to sort cells based on subtle differences. To find out more, Drug Target Review’s Victoria Rees spoke with Dr Peter O’Toole, Head of Imaging and Cytometry and Dr…
whitepaper
Product hub: High-content 3D confocal imaging of live cell clusters
Learn about the high-content analysis system that provides high-quality three-dimensional imaging for enhanced live cell analysis.
article
Nanobodies that bind a component of the SARS-CoV-2 replication complex
Professors Piergiorgio Percipalle and Gennaro Esposito summarise their study which revealed two nanobodies that could inhibit a non-structural protein of SARS-CoV-2.
article
Drug Target Review Flow Cytometry ebook 2021
This ebook includes articles on flow cytometry in drug discovery and how it is applied to leishmaniasis research. Also included is a piece on how flow cytometry is being used to support the translational research of immuno-oncology therapies.
article
Drug Target Review – Issue 4 2021
This issue includes articles that discuss the development of long-term 3D tissue cultures from human biopsy samples, the application of flow cytometry in drug discovery and automation for upstream processing in a biologics manufacturing environment. Also included are features on informatics, proteomics and CRISPR.
whitepaper
Brochure: Biologics workflow solutions brochure
Biologics solutions from discovery to manufacturing.
news
Label-free technique could revolutionise tissue analyses
A new high-resolution virtual microscopy technique enables the rapid visualisation of tissue, paving the way for histopathology analysis during surgery.