news
A new generation of pain relief
Researchers have developed a new generation of pain relief drugs that only target the affected area, with the help of computer simulations...
List view / Grid view
Informatics
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Expert view: Screen everything. See everything.
Explore the full kinetic and epitope diversity of large antibody libraries with high throughput Array SPR (Surface Plasmon Resonance).
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Flow Cytometry In-Depth Focus 2018
Flow cytometry has played a key role in drug development, largely due to its ability to measure up to twenty parameters on single cells or particles suspended in a fluid stream. Conor Fitzpatrick discusses how the rise of high-throughput flow cytometry has contributed to the advancements in drug discovery...
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Expert view: GMP proteins for therapeutic manufacturing: combining consistency, safety, and supply
Cell therapies offer revolutionary new approaches for treating humandisease. Most of these treatments use GMP cytokines and growthfactors for the differentiation, expansion, and maintenance of cells.It is critical that GMP protein suppliers offer the optimal combinationof consistency, safety, and stable supply chain.
whitepaper
Application Note: Evaluating the specificity and potency of PD-1 and PD-L1 blocking antibodies using AlphaLISA human and mouse PD-1/PD-L1 binding kits
Cancer immunotherapy utilises components of the immune system to treat cancer patients. These therapies are designed to work with a patient’s immune system to increase native anti-tumour responses. One type of immunotherapy relies on antibodies to bind to and inhibit the function of proteins expressed by the cancer cell...
news
How challenges including Brexit, inadequate funding & insufficient sample sizes hinder rare disease research
SMi Reports: 8th Annual Orphan Drugs and Rare Diseases Conference to bring together pharmaceutical companies, non-profit organisations and orphan drug developers to explore alliances and facilitate progress.
news
Researchers successfully use AI to facilitate dynamic dosing for metastatic cancer
Scientists have harnessed a powerful artificial intelligence (AI) platform, CURATE.AI, to successfully treat a patient with advanced cancer by completely halting disease progression, representing a big step forward in personalised medicine.
news
Computational analysis identifies a new clinical phenotype of severe malaria
Researchers have applied a computational analysis based on networks in order to identify biologically relevant phenotypes apart from those currently defined by the WHO...
news
Scientists discover over 7,000 effective antibiotic combinations
Researchers discovered effective antibiotic combinations using four or five drugs, despite claims that combinations of three or more won't work...
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Drug Target Review – Issue 3 2018
In this issue: pharmacological targeting of mitochondrial dysfunction in Parkinson’s disease, the evolving role of three dimensional in-vitro cell culture techniques in drug discovery, and NGS: hunting mysterious ‘Dark Matter Genome’ towards rewriting the rules of genetic diseases.
news
AI system detects cancer tumours missed by conventional diagnostics
Computer engineers have 'taught' a computer to identify tiny specs of lung cancer in CT scan images, often missed by radiologists...
news
Effective approach to optimising medicinal molecules
Computational methods accelerates and automates the process of optimisation of candidate molecules before performing preclinical trials...
webinar
Recent advances in diagnostics and treatments – from small molecules to cellular therapies
14 August 2018 | By Bio-Techne
With recent advances in medicine, cellular therapies are one step closer to becoming a reality where re-programmed cells, tissues and organs can be used as therapeutic agents. This webinar discussed the journey of medical treatments from small molecule to cellular therapies...
