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A new generation of pain relief

10 September 2018 | By Drug Target Review

Researchers have developed a new generation of pain relief drugs that only target the affected area, with the help of computer simulations...

Yasmina Noubia Abdiche, PhD Chief Scientific Officer, Carterra® Inc.

article

Expert view: Screen everything. See everything.

10 September 2018 | By Yasmina Noubia Abdiche (Carterra)

Explore the full kinetic and epitope diversity of large antibody libraries with high throughput Array SPR (Surface Plasmon Resonance).

article

Flow Cytometry In-Depth Focus 2018

7 September 2018 | By Drug Target Review

Flow cytometry has played a key role in drug development, largely due to its ability to measure up to twenty parameters on single cells or particles suspended in a fluid stream. Conor Fitzpatrick discusses how the rise of high-throughput flow cytometry has contributed to the advancements in drug discovery...

article

Expert view: GMP proteins for therapeutic manufacturing: combining consistency, safety, and supply

6 September 2018 | By Tim Manning (Bio-Techne)

Cell therapies offer revolutionary new approaches for treating humandisease. Most of these treatments use GMP cytokines and growthfactors for the differentiation, expansion, and maintenance of cells.It is critical that GMP protein suppliers offer the optimal combinationof consistency, safety, and stable supply chain.

whitepaper

Application Note: Evaluating the specificity and potency of PD-1 and PD-L1 blocking antibodies using AlphaLISA human and mouse PD-1/PD-L1 binding kits

5 September 2018 | By Cat Lautenschlager, Dawn Nida, Jeanine Hinterneder, Lauren Berstler

Cancer immunotherapy utilises components of the immune system to treat cancer patients. These therapies are designed to work with a patient’s immune system to increase native anti-tumour responses. One type of immunotherapy relies on antibodies to bind to and inhibit the function of proteins expressed by the cancer cell...

news

How challenges including Brexit, inadequate funding & insufficient sample sizes hinder rare disease research

4 September 2018 | By SMi Group

SMi Reports: 8th Annual Orphan Drugs and Rare Diseases Conference to bring together pharmaceutical companies, non-profit organisations and orphan drug developers to explore alliances and facilitate progress.

news

Researchers successfully use AI to facilitate dynamic dosing for metastatic cancer

4 September 2018 | By Drug Target Review

Scientists have harnessed a powerful artificial intelligence (AI) platform, CURATE.AI, to successfully treat a patient with advanced cancer by completely halting disease progression, representing a big step forward in personalised medicine.

news

Computational analysis identifies a new clinical phenotype of severe malaria

4 September 2018 | By Drug Target Review

Researchers have applied a computational analysis based on networks in order to identify biologically relevant phenotypes apart from those currently defined by the WHO...

news

Scientists discover over 7,000 effective antibiotic combinations

3 September 2018 | By Iqra Farooq (Drug Target Review)

Researchers discovered effective antibiotic combinations using four or five drugs, despite claims that combinations of three or more won't work...

article

Drug Target Review – Issue 3 2018

3 September 2018 | By Drug Target Review

In this issue: pharmacological targeting of mitochondrial dysfunction in Parkinson’s disease, the evolving role of three dimensional in-vitro cell culture techniques in drug discovery, and NGS: hunting mysterious ‘Dark Matter Genome’ towards rewriting the rules of genetic diseases.

Company Profile

Beckman Coulter, Inc.

news

AI system detects cancer tumours missed by conventional diagnostics

23 August 2018 | By Iqra Farooq (Drug Target Review)

Computer engineers have 'taught' a computer to identify tiny specs of lung cancer in CT scan images, often missed by radiologists...

Company Profile

SB Drug Discovery Ltd

news

Effective approach to optimising medicinal molecules

15 August 2018 | By Drug Target Review

Computational methods accelerates and automates the process of optimisation of candidate molecules before performing preclinical trials...

webinar

Recent advances in diagnostics and treatments – from small molecules to cellular therapies

14 August 2018 | By Bio-Techne

With recent advances in medicine, cellular therapies are one step closer to becoming a reality where re-programmed cells, tissues and organs can be used as therapeutic agents. This webinar discussed the journey of medical treatments from small molecule to cellular therapies...

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Informatics