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CRISPR technology inactivates cancer mutations

1 September 2016 | By Niamh Louise Marriott, Digital Content Producer

CRISPR/Cas9 is likely one of the most revolutionary tools in biotechnology, with tremendous implications for a broad range of biological and medical disciplines. As programmable scissors this technology allows cleavage of DNA at predefined sites in the genome of cells...

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CRISPR gene editing could treat sickle cell disease

15 August 2016 | By Niamh Louise Marriott, Digital Content Producer

Foetal haemoglobin lacks beta sub-units and has gamma sub-units instead. Thus, beta-thalassemia or SCD–associated mutations, which impair the production or function of the beta sub-unit, do not cause problems with foetal haemoglobin, which can transport oxygen effectively in adults...

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Flu vaccines fail to protect obese mice

8 August 2016 | By St. Jude Children’s Research Hospital

Using vaccines prepared from killed viruses, the scientists targeted an influenza A H1N1 seasonal flu strain, finding that obese mice are not protected against influenza infections through vaccines, raising concerns about vaccine response in obese humans, who are known to be at an increased risk for severe flu...

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Leukaemia study takes aim at therapy resistant proteins

28 July 2016 | By Caleb Radford, The Lead

Assessing a patient's levels of the P-glycoprotein soon after they start receiving Glivec therapy will help to predict that patient’s long-term response to the leukaemia drug, according to new research from SAHMRI and the University of Adelaide...

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GlaxoSmithKline to invest £275 million in UK

27 July 2016 | By Niamh Louise Marriott, Digital Content Producer

The investment will be used for manufacturing of new respiratory and biopharmaceuticals, to be exported outside the UK to global markets...