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Molecular biology

ADHD - diagnosis written on a white piece of paper. Syringe and vaccine with drug

news

Blood pressure drug shows promise in ADHD symptom reduction

26 February 2025 | By Drug Target Review

A study by the University of Surrey suggests that amlodipine, a common blood pressure medication, could be repurposed as a safer, more accessible treatment for ADHD. This offers a promising alternative to current medications and highlights the potential of drug repurposing in advancing treatment options.

CAR T cell therapy in Non-hodgkin lymphoma (NHL) - closeup view 3d illustration

article

New therapy shows promise in strengthening CAR-T responses

25 February 2025 | By Drug Target Review

CAR-T therapy has shown effectiveness in cancer treatment, but relapse often occurs due to limited cell persistence. New strategies aim to improve CAR T-cell durability for longer lasting remission.

Neuronal inclusions in Huntington's disease, 3D illustration. Inclusions are composed of mutated huntingtin protein, they are initially formed at axons and dendrites, then migrate to nuclei of neurons

news

DNA repair genes drive Huntington’s disease, UCLA study finds

21 February 2025 | By Drug Target Review

A new UCLA study reveals that DNA mismatch repair genes play a crucial role in Huntington’s disease by driving neuronal damage and motor impairments. Targeting these genes, especially Msh3 and Pms1, could offer promising therapeutic avenues for the disease.

article

Experts explore the future of iPSC-based cell therapies

19 February 2025 | By

Discover the transformative potential of iPSC-based therapies in regenerative medicine, alongside their challenges including scalability, safety and targeted delivery.

Genetic brain disorders, conceptual 3D illustration. Mutations in the DNA leading to brain diseases. Neurogenetics, neurodegenerative disorders

news

Study identifies new genetic targets for neuropsychiatric diseases

18 February 2025 | By Drug Target Review

Scientists identify thousands of novel enhancers linked to neuronal differentiation and neuropsychiatric disorders, offering new pathways for drug discovery and potential therapeutic targets.

article

Landmark study aims to detect Parkinson’s before symptoms

17 February 2025 | By Drug Target Review

Grifols' Chronos-PD initiative leverages its extensive plasma repository to identify early biomarkers of Parkinson's disease, advancing early detection and contributing to the development of innovative therapies.

news

ITM-11 boosts survival in neuroendocrine tumour trial

3 February 2025 | By Drug Target Review

A new targeted radiotherapy offers hope for patients with rare neuroendocrine tumours, demonstrating a significant improvement in progression-free survival in a key clinical trial.

news

New study shows CGM data can predict diabetes complications

24 January 2025 | By Drug Target Review

UVA researchers found that continuous glucose monitor data can predict nerve, eye, and kidney damage in type 1 diabetes.

article

FDA’s Project Optimus: A new era in oncology drug dosing

20 January 2025 | By Dr Romillie Cruz

Explore how FDA’s Project Optimus is reshaping oncology drug dosing strategies, with insights on precision medicine, adaptive trial designs, and the role of CROs in optimising patient outcomes.

Conceptual photo about Rett syndrome with written text.

news

Rett syndrome discovery could lead to better treatments

17 January 2025 | By Drug Target Review

Researchers have identified early molecular changes in Rett syndrome that could lead to improved treatments for the condition.

Doctor holds psycho neurological pills for brain in hands

news

LB Pharmaceuticals announces positive schizophrenia trial data

15 January 2025 | By Drug Target Review

LB Pharmaceuticals announced positive Phase II results for LB-102, showing significant symptom improvement in schizophrenia with a favourable safety profile.

human brain, dna structure with glass helix on blue background

news

Study reveals how neurotransmitters influence brain gene expression

14 January 2025 | By Drug Target Review

A new study demonstrates how neurotransmitters affect brain gene expression, offering potential therapeutic insights for circadian rhythm disorders.

news

New painless vaccine technology targets viruses

13 January 2025 | By Drug Target Review

Learn how Kindeva and Emervax are advancing vaccine delivery with painless, needle-free technology designed to improve accessibility and uptake worldwide.

news

Innovative lupus treatment under investigation at Virginia Tech

10 January 2025 | By Drug Target Review

A Virginia Tech student is investigating new treatments for lupus, an autoimmune disease that affects millions worldwide.

news

New genetic mechanism could lead to RNA therapies for mental health

9 January 2025 | By Drug Target Review

Researchers at the Medical University of South Carolina have discovered a key genetic mechanism that could lead to RNA-based therapies for psychiatric disorders triggered by emotional experiences.

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Molecular biology