news
TREM2 regulation to prevent neurodegeneration is possible, study shows
Scientists used a synthetic thyroid hormone in mice to regulate the TREM2 gene implicated in diseases such as Alzheimer’s and Parkinson’s.
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Omics
news
Researchers reveal potential cause of COVID-19 aftereffect in children
Scientists have uncovered an important clue to the COVID-19-related multisystem inflammatory syndrome in children (MIS-C).
news
Inhibiting REST gene could be clue to new diabetes treatments
A study has shown that inhibiting the REST gene boosted insulin-producing cells during early pancreas development in animals.
news
Frameshifting method could be a new mast cell cancer treatment
Frameshifting therapy has been shown to reduce the number of mast cells by “mutating” mRNA, showing promise as a new cancer treatment.
whitepaper
Application note: High-content phenotypic profiling using the cell painting assay
The cell painting assay uses up to six fluorescent dyes to label and visualize a variety of subcellular structures at the single cell level.
news
Prime editing method corrects cystic fibrosis in stem cells
A team of scientists used a CRISPR-Cas9 technique known as prime editing to correct cystic fibrosis in cultured human stem cells.
news
Molecular insights into LSCC may lead to new drug targets
New insights into lung squamous cell carcinoma (LSCC) have emerged from a proteogenomic study, leading to the identification of potential drug targets.
article
Spatial genomic and transcriptomic imaging in drug discovery
In this interview, read about the compilation of a new high-resolution cell atlas of the mouse brain using spatial genomics and transcriptomics.
news
Researchers reveal how microbiome bacteria adapt through transmission
Scientists have used genetic sequencing to demonstrate how the transmission of gut bacteria influences its evolution and functions, which could effect human health.
news
Artificial intelligence may reveal how microbiome affects vaccine response
Researchers have been using artificial intelligence to study how the microbiome interacts with the human system to improve vaccine response.
news
Therapeutic target for aggressive cancers discovered through CRISPR
The RNA-modifying protein METTL1 could be targeted to treat some types of aggressive cancers, including brain, blood and kidney.
news
Prize winner uncovers how microbiome can combat neurodegeneration
Eran Blacher has won the NOSTER & Science Microbiome Prize for discovering the link between the microbiome and neurodegenerative diseases.
news
CRISPR-Cas9 used to prevent Fuchs’ corneal dystrophy in mice
Scientists have shown that start codon disruption with CRISPR-Cas9 gene editing can prevent Fuchs’ corneal dystrophy in mouse models.
news
Sunlight shown to trigger DNA mutation that causes melanoma
New research found mutations that cause melanoma result from a chemical conversion in DNA fuelled by sunlight, undermining previous theories.
podcasts
Episode 2 – SARS-CoV-2 variants with Dr Justin Lee, CDC, Professor Vasan, CSIRO & Dr Chantal Vogels, Yale School of Medicine
Listen to this podcast to discover how SARS-CoV-2 variants are sequenced and why PCR assays could provide an alternative for resource-constrained places.
