article How AI is accelerating the future of precision medicine 12 January 2024 | By Ellen Capon (Drug Target Review) Dr Ketan Patel, Clarivate, shares his insights about the use of Real-World Data and genomic biomarker data and discusses how researchers can use these to better detect and diagnose diseases.
news Unexpected patterns in DNA mutations identified 11 January 2024 | By Drug Target Review Disruptions in TP53 and RB1 are key influencers that cause changes in the risk of mutations across chromosomes.
news Using proteomics to predict long-term disability outcomes in MS 10 January 2024 | By Drug Target Review Data from protein analyses, combined with data from patient journals, enabled the discovery of proteins that predict disease progression.
article A Guide to DNA Damage Response and Innate Immunity 10 January 2024 | By BellBrook Labs In this guide, we provide an overview of the DDR and innate immune pathway and describe Transcreener Assays and Assay Systems for key targets.
news Discovery enables further investigation into new ligases 4 January 2024 | By Drug Target Review Researchers have developed a new PROTAC that activates the protein degradation system and binds to a previously inaccessible ligase.
article Drug Target Review – Issue 4 2023 21 December 2023 | By A new Drug Target Review issue is now ready to download! This issue features articles on CRISPR, personalised medicine and screening.
news New algorithm identifies a novel CRISPR-Cas system 24 November 2023 | By Drug Target Review Findings of rare CRISPR-linked gene modules and a novel CRISPR-Cas system have promising implications for genomic therapeutics.
news Incorporating microglia into brain organoids 16 November 2023 | By Drug Target Review iPS-cell-derived microglia in brain organoids have enabled scientists to understand early brain development and microglia-associated disease.
news Protective mutation found in kidney disease gene 17 October 2023 | By Drug Target Review A new discovery about a different protective genetic mutation in apolipoprotein L1 could have major implications for kidney health.
whitepaper ebook: Maximizing preclinical confidence in target efficacy and safety 27 September 2023 | By Euretos This ebook outlines Euretos’ approach to target discovery and indication expansion. Whilst also discussing data-driven target selection.
article Drug Target Review – Issue 3 2023 14 September 2023 | By Drug Target Review A new Drug Target Review issue is now ready to download! This issue features articles on vaccine development, artificial intelligence and organoids.
news Novel based editors developed 4 September 2023 | By Drug Target Review Researchers have developed a novel based CRISPR-free base editing system named CyDENT, which enables precise base editing.
webinar Bridging the gap: using organ-on-a-chip as an experimental tool to develop (cost) effective therapeutics 25 July 2023 | By CN Bio The webinar will explore primary concerns in drug discovery development and why drugs fail.
news A structural insight into HIV drug-resistance mechanisms 24 July 2023 | By Izzy Wood (Drug Target Review) New Salk Institute, US, research could lead to the development of new HIV therapeutics that overcome resistance to existing drugs.
news Rare cause of hereditary cancer missed in younger patients 14 July 2023 | By Izzy Wood (Drug Target Review) US investigators find that some cases of Lynch syndrome, the most common hereditary cancer condition, are missed in younger patients under current screening guidelines.
