news Novel approach stimulates DNA repair mechanisms to combat a leading cause of autism spectrum disorders 22 May 2023 | By Izzy Wood (Drug Target Review) US researchers report promising results for fragile X syndrome, by stimulating cells' DNA repair mechanisms that could correct the inherited genetic defect associated with the disorder.
webinar Normalization of organ-on-a-chip samples for mass spectrometry based proteomics and metabolomics via dansylation-based assay 19 May 2023 | By CN Bio A discussion of the recently published paper, “Normalization of Organ-on-a-Chip Samples for Mass Spectrometry Based Proteomics and Metabolomics via Dansylation-based Assay,” and how the field can produce more replicable experiments.
news New study uncovers DNA repair mechanism in bacterial cells 19 May 2023 | By Izzy Wood (Drug Target Review) US research reveals mechanism used by bacterial cells to repair their faulty DNA, which could help scientists understand the intricacies of DNA repair processes.
news Diagnosing inflammatory diseases with synthetic peptides 18 May 2023 | By Izzy Wood (Drug Target Review) Researchers from Switzerland identify peptides that detect and measure a key biomarker in inflammatory conditions.
news New technique enables in vivo analysis of protein complexes 11 May 2023 | By Izzy Wood (Drug Target Review) Chinese researchers use a glycosidic-bond-based mass-spectrometry-cleavable cross-linker to analyse proteins in vivo.
news Computational tool gets more out of multi-omics data 8 May 2023 | By Izzy Wood (Drug Target Review) US researchers developed a next-generation computational tool called NetBID2 that can uncover difficult-to-identify proteins that drive biological processes contributing to cancer.
article CRISPR and single-cell sequencing highlight genetic variants for traits and diseases 4 May 2023 | By Drug Target Review This article highlights a new approach to address human genetics, using STING-seq which provides roadmap to identify variants and genes, enabling deeper understanding of the noncoding genome and targets for therapies
news Blocking a microRNA may prevent age-related conditions 2 May 2023 | By Izzy Wood (Drug Target Review) Conditions like chronic inflammation, muscle loss and bone loss have an elevated microRNA, US researchers attempted to block this in aged mice.
news New treatment pathway for deadly pancreatic cancers 25 April 2023 | By Izzy Wood (Drug Target Review) US scientists have used mouse models of pancreatic cancer to identify genes used by tumour cells to grow uncontrollably.
news Antimicrobial resistance identified in bloodstream by metagenomic sequencing 17 April 2023 | By Izzy Wood (Drug Target Review) University of Oxford finds rapid metagenomics can produce accurate results 18-42 hours quicker than conventional tests for antimicrobial resistance in bloodstream infections, which could save lives and reduce the misuse of antibiotics.
article Drug Target Review – Issue 1 2023 29 March 2023 | By Drug Target Review A new Drug Target Review is now ready to download! This issue features articles which explore antibodies, vaccines and assays.
whitepaper Application note: Single Cell Deposition Efficiency 23 March 2023 | By Bio-Techne Comparison of single cell dispensing efficiency between Namocell Single Cell Dispenser and limiting dilution method.
whitepaper Guide: Tips for Single Cell Isolation 14 March 2023 | By Bio-Techne Single cell isolation is a critical step for a number of workflows, and can greatly impact the success of downstream applications.
news Researchers find ancient virus genome drives autism 14 March 2023 | By Ria Kakkad (Drug Target Review) The scientists revealed in mice models that endogenous retrovirus activation increases a foetus’s susceptibility to autism.
news Research shows lipid nanoparticles are highly effective in gene therapy 9 March 2023 | By Ria Kakkad (Drug Target Review) Lipid nanoparticles have been used to encapsulate CRISPR-Cas9 and deliver it to cells in mice, where it was highly effective at knocking down expression of a target protein.
