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Screening

news

Virtual method enables screening of billions of chemical compounds

10 January 2022 | By Victoria Rees (Drug Target Review)

A new platform, named Virtual Synthon Hierarchical Enumeration Screening, has been developed by researchers to efficiently discover drugs.

news

Scientists discover compound to combat multidrug-resistant bacteria

7 January 2022 | By Mandy Parrett (Drug Target Review)

Taking a novel approach to antibiotic discovery, researchers at Rockefeller University have hit upon a promising solution to the problem of superbugs – a pervasive threat in hospitals the world over.

whitepaper

Product hub: Power your bioanalytical workflows

7 January 2022 | By Thermo Fisher Scientific – Digital Science

Learn about how Thermo Scientific™ Watson LIMS™ software can help manage bioanalytical studies, working to industry and regulatory standards for small and large molecule testing.

whitepaper

Product hub: Introducing the latest addition to Thermo Fisher Scientific’s genome editing portfolio – Invitrogen^TM TrueCut^TM HiFi Cas9 Protein!

6 January 2022 | By Thermo Fisher Scientific – Cell Biology

Read about the latest addition Invitrogen™ TrueCut™ HiFi Cas9 Protein to support your application and research goals.

podcasts

Episode 4 – LIMS systems with Tyler Pascoe & Matt Gruver, Thermo Fisher Scientific

20 December 2021 | By Drug Target Review

In this podcast, join Tyler Pascoe and Matt Gruver from Thermo Fisher Scientific as they explore the new Watson LIMS software.

whitepaper

Product hub: High-content 3D confocal imaging of live cell clusters

16 December 2021 | By Yokogawa

Learn about the high-content analysis system that provides high-quality three-dimensional imaging for enhanced live cell analysis.

whitepaper

Application note: Cell line development: accelerating process optimisation

16 December 2021 | By Sartorius AG

This study demonstrates the ease, simplicity and speed of performing multiple conditions in one experiment using Ambr 15 Cell Culture by assessing five different media compositions on two different clones.

whitepaper

Application note: Competitive high-throughput analysis of kinase inhibitor binding kinetics

16 December 2021 | By BMG Labtech GmbH

A microplate-based method for the determination of association and dissociation rate values in high throughput using a kinetic probe competition assay (kPCA).

webinar

Unlocking orphan GPCRs with an innovative forward trafficking approach

16 December 2021 | By Eurofins DiscoverX and Sanford Burnham Prebys Medical Discovery Institute

Watch this on-demand webinar to learn about orphan GPCRs as drug targets and the challenges related to lead identification.

Pills and stethoscope on blackboard with COVID-19 structure written on it

news

New platform screens for specific class of coronavirus antiviral compounds

15 December 2021 | By Anna Begley (Drug Target Review)

Researchers developed a platform that can rapidly screen thousands of compounds to identify potential antiviral drugs to treat coronaviruses.

news

Team identifies lead compound to potentially treat schistosomiasis

14 December 2021 | By Victoria Rees (Drug Target Review)

Researchers have found a quinoxaline-core containing, non-genotoxic lead compound that could treat schistosomiasis following optimisation.

news

Lead compound for potential treatment of acute kidney injury identified

13 December 2021 | By Victoria Rees (Drug Target Review)

A new 6-chromanol-derived compound named SUL-138 has shown promise in animal models at treating acute kidney injury.

news

“Overlooked” FAM72A gene shines light on antibody production

3 December 2021 | By Anna Begley (Drug Target Review)

Scientists used a new screen to identify FAM72A as a cause of mutagenesis that affects antibody development in COVID-19 and cancer.

news

Novel screening method identifies lead molecule for GPCR dimerisation

30 November 2021 | By Anna Begley (Drug Target Review)

The new high-throughput screening method identified nine lead molecules for rhodopsin dimerisation that may lead to next-generation medicines.

news

“Sleeping” cancer cells could prevent tumour metastasis

25 November 2021 | By Anna Begley (Drug Target Review)

A new study prevented the growth of metastatic tumours in mice by forcing cancer cells into a dormant state, pointing to novel treatments.

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Screening