news
Small molecules to reduce cellular stress identified by HTS
Scientists used high throughput screening (HTS) to identify molecules that protect against cellular stress in murine skin cells.
List view / Grid view
Screening
news
Platform for hit-to-lead identification of antibacterial lysins developed
A group of scientists has created a novel high-throughput hit-to-lead development platform to identify engineered antibacterial lysins.
news
Hit-to-lead from small molecule library screens can identify new vaccine adjuvants
Researchers have screened small molecule libraries and then applied hit-to-lead approaches to discover effective vaccine adjuvants.
whitepaper
Application note: Monitor mitochondria dynamics and phenotype with high-content imaging
There has been growing interest in using high-content imaging methods for studying mitochondria.
news
Epigenetic marks could be the target of future Alzheimer’s therapies
New findings suggest that late-onset Alzheimer's Disease (AD) is driven by epigenetic changes in the brain.
![Glioblastoma Multiforme (GBM) cells in culture [Credit: Dr Jin-Min Nam].](https://www.drugtargetreview.com/wp-content/uploads/glioblastoma-cells-750x500.jpg)
![Glioblastoma Multiforme (GBM) cells in culture [Credit: Dr Jin-Min Nam].](https://www.drugtargetreview.com/wp-content/uploads/glioblastoma-cells-e1601552379990.jpg)
news
Identifying radioresistance drivers in glioblastoma multiforme
According to researchers, Rab27b and epiregulin contribute to the development of radioresistance and could be targeted to improve glioblastoma patient survival.
news
Novel RNA-targeting molecule can halt SARS-CoV-2 replication
The C5 compound targets the frameshifting element that allows SARS-CoV-2 to effectively replicate and marks the genome for destruction to stop the infection spreading.
news
Hit-to-lead predicted to be fastest-growing process in drug discovery market
The high level of outsourcing of hit-to-lead processes will make it the fastest-growing segment of the drug discovery service market, a new report says.
video
Video: ImageXpress Pico Virtual Tour
Explore this virtual tour of the ImageXpress Pico Automated Cell Imaging System from Molecular Devices, including hardware and software.
news
Why do some patients develop COVID-19 pneumonia?
Scientists reveal that some patients who develop severe COVID-19 symptoms mount ineffective immune responses due to a lack of type I interferons, either through genetic mutation or inactivation by auto-reactive antibodies.
whitepaper
ebook: From ELISA to epigenetics with HTRF
Overcome HTRF detection challenges with optimised microplate reader settings and simplified analysis.
news
Natural pigment could transform long-term toxicology studies
A natural pigment from Monascus purpureus can be used to stain cells and distinguish between live and dead ones in toxicology studies.
video
Video: ImageXpress Micro Confocal Virtual Tour
Explore this virtual tour of the ImageXpress Micro Confocal High-Content Imaging System from Molecular Devices, including hardware and software.
webinar
Next generation strategies for cancer immunotherapy
24 September 2020 | By PerkinElmer
During this on-demand webinar, two leading researchers will discuss their innovative approaches to developing novel opportunities for immunotherapy treatments.
whitepaper
Webinar: Optimised workflow for rapid identification of neutralising antibodies against viral particles
Helping in the race to identify effective neutralising antibodies against the spike protein of SARS-CoV-2 virus as the COVID-19 global death rate continues to rise.