Screening

ebook: Fluorescence polarization assays

30 June 2023 | By BPS Bioscience

This ebook outlines the basics of fluorescence polarization and discusses the advantages and limitations of FP-based biochemical assays.

Cardiac and vascular safety liabilities using totality of evidence approach

27 June 2023 | By Eurofins Discovery

US-FDA recommend integration of both preclinical (S7B) and clinical (E14) data to improve risk assessment, reduce reliance on TQT clinical studies, streamlined drug-development, simplified decision-making processes, effective risk-communication.

Drug Target Review Screening eBook 2023

27 June 2023 | By

In this eBook, uncover the transformative potential of AI/ML in single-cell technologies and gain insights into disease progression.

Drug Target Review – Issue 2 2023

27 June 2023 | By Drug Target Review

A new Drug Target Review issue is now ready to download! This issue features articles on cell and gene therapy, imaging and screening.

ebook: Choosing the right assay for PARP

20 June 2023 | By BPS Bioscience

This eBook describes different types of assays used to evaluate PARP activity and screening for specific inhibitors.

Video: Using luciferase reporter cell lines for HTS readouts

30 May 2023 | By BPS Bioscience

This video reviews the uses and advantages of reporter cell lines in the context of cellular research and drug discovery.

ebook: Advances In Cell Imaging and Retrieval

22 May 2023 | By Drug Target Review

Unleash the power of drug discovery with this FREE ebook supported by Sartorius! Explore the limitless potential of CRISPR applications and single cell sequencing for drug discovery. Access exclusive insights from industry leaders and stay ahead of the curve with the latest trends. Don't miss out on this opportunity to…

Revvity

ebook: TR-FRET assay kits simplify & accelerate drug discovery

3 May 2023 | By BPS Bioscience

This ebook provides basic principles of the TR-FRET technology and shows examples of how assay design can drive drug discovery.

ebook: Never Miss A Hit – Unleash Your Drug Discovery With A Label-Free Playlist

17 April 2023 | By Drug Target Review

Get ready to dive into the cutting-edge world of hit-to-lead drug discovery. Look no further than our latest FREE ebook, which explores label-free HTL technologies. Featuring the latest research from leading academics and pharmaceutical companies, including GlaxoSmithKline, Rosalind Franklin Institute and Francis Crick Institute.

Combination therapy prevails against BET inhibitor resistance

13 April 2023 | By Taylor Mixides (Drug Target Review)

St. Jude Children's Research Hospital, US, scientists created a new combination therapy method to tackle drug resistance in a type of leukaemia with KMT2A gene rearrangement.

Webinar: The Role of Neuronal Metabolism in Early Drug Discovery

4 April 2023 | By Agilent

Learning about the mitochondrial role in a neurodegenerative disorder.

Researchers develop screening model to evaluate potential cervical cancer drugs

4 April 2023 | By Ria Kakkad (Drug Target Review)

Oregon State University researchers have developed a screening model for rapid testing of multiple drug compounds, using a 3D cellular platform.

Assay performance and the Z’-factor in HTS

30 March 2023 | By Dr Matthew Lloyd (University of Bath)

Matthew Lloyd from the University of Bath reveals the importance of the Z-factor and Z’-factor in high-throughput screening, and how they can be used to determine assay performance, perform quality control on the screen, and identify active compounds.

De-risking drugs in multiplex assays before progressing to clinical trials

30 March 2023 | By Dr Sheraz Gul (Fraunhofer Institute)

Sheraz Gul, Head of Assay Development and Drug Repurposing at the Fraunhofer Institute, discusses the importance of performing comprehensive multiplex spatial and temporal profiling of drugs in pre-clinical research to decrease the risk of potentially undesirable events in later clinical studies.