Screening

Skin test detects prion infection before symptoms appear

23 January 2019 | By Iqra Farooq (Drug Target Review)

Researchers have developed a method of using skin samples to diagnose prion infections - even before they establish themselves...

Targeted oral treatments for severe asthma

22 January 2019 | By Iqra Farooq (Drug Target Review)

Researchers are aiming to identify whether antibiotics could be used to treat severe asthma in place of steroids which often have unwanted side effects...

Catching lung cancer early using molecular profiling

22 January 2019 | By Iqra Farooq (Drug Target Review)

Researchers have identified how they can differentiate between lesions in the airways that are benign and those that could become cancerous...

Chemical tags make differences in cell fate and gene expression

18 January 2019 | By Iqra Farooq (Drug Target Review)

Scientists from Spain have identified the specific roles of chemical tags in mammalian development and cancer in controlling genes...

Intellicyt^® T Cell Activation Cell and Cytokine Profiling Kit

17 January 2019 | By IntelliCyt, a Sartorius Company

Multiplexed approach to measure T-cell activation, proliferation and quantify cytokine release in a single well

CRISPR repurposed to develop better antibiotics

14 January 2019 | By Iqra Farooq (Drug Target Review)

Mobile-CRISPRi could be used to guide gene expression, in turn control levels of proteins produced, enabling scientists to identify key antibiotic targets...

Whitepaper: The most important mouse in the world: the utility and applications of C57BL/6 models

10 January 2019 | By Taconic Biosciences

Learn everything you need to know about the most widely-used mouse in biomedical research with this free whitepaper.

‘Activating’ the immune system against cancer

8 January 2019 | By Drug Target Review

A study has found that the immune system can be harnessed to fight cancer cells in a particularly efficient manner, one also effective in lung cancer...

AI used to diagnose diabetic eye disease

8 January 2019 | By Iqra Farooq (Drug Target Review)

Artificial Intelligence has been used to cost-effectively diagnose diabetic-related eye disease automatically with far more accuracy than current methods...

Whitepaper: Application of CRISPR/Cas to the generation of genetically engineered mice

7 January 2019 | By Taconic Biosciences

Learn how the continued development of CRISPR gene editing technologies opens fresh possibilities for in vivo model design.

Using machine learning to predict symptoms

2 January 2019 | By Iqra Farooq (Drug Target Review)

Machine learning could, in future, be the way that clinicians decide on particular courses of treatments for patients affected by cancer...

Application note: Rapidly isolate high-producing clones

21 December 2018 | By Sphere Fluidics Ltd.

Find out how to streamline Cell Line Development by identifying high-producing clones with monoclonality assurance in one day.

Sphere Fluidics Ltd.

Application note: GABA_A Receptors

11 December 2018 | By SB Drug Discovery

SB Drug Discovery shows the validation of fluorescence and automated electrophysiology assays designed to assess agonists, antagonists and allosteric modulators of these receptors, culminating in a high-throughput electrophysiology assay suited to assessing multiple GABAA receptor subtypes on a single assay plate.

Webinar highlights: Integrated fragment based approach reveals enzymatic inhibitors with potential therapeutic application

10 December 2018 | By NanoTemper Technologies

This webinar, held on 25 October 2018, presented the results from integrated fragment-based approaches for Indoleamine 2,3 dioxygenase 1 (IDO1), an enzyme widely recognised as a drug target for the development of immunotherapeutic small molecules in oncology, unveiling the first ligands able to modulate non-catalytic signalling.