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Jiankun Lyu hopes to use algorithms to find improved drugs by screening chemicals that may look different to a protein’s known ligands but work in a similar way.
Using an AI algorithm that models drug and target protein interactions, researchers achieved up to 97 percent accuracy in identifying promising drug candidates.
Compendium of iQue® advanced flow cytometry platform application posters: Antibody discovery and immuno-oncology.
Discover how picodroplet microfluidic technologies can identify and isolate 'hit' cells, quantify varying concentrations of antigen-specific antibodies and much more.
Researchers have developed a new method that enables high-throughput screening of Huntington’s disease organoids.
In the search for a rapid, easy way to identify drugs to fight SARS-CoV-2, researchers from across the US came together to develop and apply a high-throughput ADP-ribosylhydrolase assay, ADPr-Glo. Here, Dr Veronica Busa and Dr Anthony Leung from Johns Hopkins University describe the ADPr-Glo assay and how it can be…
In this Q&A, Immunexpress Chief Executive Officer Dr Rolland Carlson and Chief Scientific Officer Dr Richard Brandon discuss key aspects for molecular diagnostic discovery and development platforms, including how to best leverage microarray and next-generation sequencing (NGS) tools.
Learn how R&D Systems™ Avi-tag biotinylated proteins can be used as an alternative to amine biotin coupling in surface plasmon resonance experiments.
Researchers have used a high-throughput assay to screen for potential small molecule SARS-CoV-2 replication inhibitors.
A report has shown that the immuno-oncology drug discovery outsourcing market is set to be worth $2563 million by 2030.
This ebook explores the role of binding kinetics in drug discovery, current methods for kinetic parameter analysis, novel approaches and applications.
Researchers screened biologically active small molecules, finding several compounds with the ability to induce training effects on macrophages.
A report has found that rapidly evolving R&D infrastructure will help to drive the high-content screening market forwards.
Included in this ebook are pieces on how an assay for the detection of sepsis was developed and a new high-throughput assay that could reveal new drugs to fight COVID-19.
In this issue are articles on synthetically engineered bacteria to deliver therapeutics, how single-molecule fluorescence resonance energy transfer was used to image GPCRs and a new assay to identify coronavirus drugs. Also included are pieces on vaccine development, monoclonal antibodies and neuroscience.
