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Stem Cells

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Scientists use stem cells to generate rudimentary kidney organoids

16 June 2021 | By Victoria Rees (Drug Target Review)

Researchers have developed kidney organoids that resemble the collecting duct system, using ureteric bud progenitor cells.

article

Drug Target Review – Issue 2 2021

14 June 2021 | By Drug Target Review

This issue includes articles on novel AAV vectors to deliver ocular gene therapy, how phenotypic models of disease are being used in covalent fragment screening and the challenges and opportunities presented by automation in the life sciences. Also in this issue are features on stem cells, antibodies and hit-to-lead.

article

Off-the-shelf T-cell therapy from gene edited stem cells

10 June 2021 | By Dr Jo Brewer (Adaptimmune)

Dr Jo Brewer outlines research into allogeneic products by gene editing stem cells, which has the potential to build a broad family of multiple immune cell types, including T-cell therapies.

news

Tiny implant cures diabetes in mice without triggering immune response

7 June 2021 | By Victoria Rees (Drug Target Review)

Scientists have developed an implant that releases insulin-secreting cells which has shown success at treating diabetes in mice.

whitepaper

ebook: How automation makes labs more efficient

4 June 2021 | By SPT Labtech

We discuss how liquid handling automation supports drug discovery workflows & highlight opportunities to improve the efficiency and quality of these.

Application note: Western blot & IP assay to verify antibody specificity

whitepaper

Application note: Western blot & IP assay to verify antibody specificity

1 June 2021 | By Bethyl Laboratories

Learn about a practical, high-throughput method for validating the target-specificity of antibodies for the application of western blot.

whitepaper

ebook: Accelerate vaccine development

13 May 2021 | By Molecular Devices

Our comprehensive portfolio suite is designed to optimize your productivity to get safe and efficacious vaccines and therapeutics to market faster.

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Five of the latest developments in 3D bioprinting

13 May 2021 | By Victoria Rees (Drug Target Review)

Drug Target Review brings you five of the most recent developments in three-dimensional (3D) bioprinting.

Ncardia Case Study on Parkinson's Disease

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Case study: Parkinson’s disease modelling for drug discovery

11 May 2021 | By Ncardia

The development of a Parkinson’s disease model, using hiPSC-derived neural cells, to assess alpha-synuclein pre-formed fibril-induced toxicity.

news

Stem cell-based vaccine protects mice against pancreatic cancer

7 May 2021 | By Victoria Rees (Drug Target Review)

Researchers have developed a vaccine using stem cells that protected mice injected with pancreatic cancer cells from developing tumours.

news

Small-molecule cocktail could improve use of stem cells in treatments

4 May 2021 | By Victoria Rees (Drug Target Review)

Researchers have shown that Chroman 1, Emricasan and trans-ISRIB, in combination with polyamines, are effective at protecting induced pluripotent stem cells from stress.

news

New imaging method visualises respiratory activity of cell models

3 May 2021 | By Victoria Rees (Drug Target Review)

Researchers have created a new imaging technique called electrochemiluminescence to visualise multiple spheroids with a single shot.

video

Video: Imaging and analysis of a 3D airway organoid model

29 April 2021 | By Molecular Devices

In this short video we show an example of a 3D airway organoid model along with some interesting ways to get the most out of this type of assay.

news

New 3D organoid model of pancreas developed from human stem cells

29 April 2021 | By Victoria Rees (Drug Target Review)

Researchers have developed the first 3D organoid models of the pancreas that includes both the acinar and ductal structures.

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Stem cell therapy repairs damage from dementia in mouse brains

22 April 2021 | By Victoria Rees (Drug Target Review)

Researchers have developed a stem cell therapy that could treat the damage caused by dementia by launching a repair response.

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Stem Cells