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Whitepaper: Why BioPharma Lifecycle Management?
In this whitepaper we explore some of the major bottlenecks in the development lifecycle and the current barriers to effective digital transformation.
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Stem Cells
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In vitro model could aid the development of fatty liver disease treatments
The patient-derived model of non-alcoholic fatty liver disease (NAFLD) accurately reproduced the complex human metabolic pathways involved in the development of the disease.
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Scientists develop potential ‘smart’ stem cells made from human fat
Using a new compound mixture, researchers have created adaptive and regenerative stem cells from human fat cells.
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ebook: The organoid culture handbook
This tissue-specific handbook brings you key publications, in-house protocols and troubleshooting recommendations for your organoid cell culture.
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New tissue engineering process brings laboratory-grown organs one step closer
Researchers have developed a new technique that that could one day enable us to grow fully functional human organs in the laboratory.
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Novel human alveolar tissue model could help COVID-19 drug development
Researchers will use the in vitro model to study how respiratory viruses, like SARS-CoV-2, cause Acute Respiratory Distress Syndrome (ARDS) and develop potential interventions.
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Brain injury may drive the development of cancer
A new study reveals that the healing process following a brain injury could initiate the growth of glioblastoma cancers.
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New embryonic stem cell type could advance regenerative medicine
Scientists suggest that research using XPSCs, an intermediate form of embryonic stem cell, could help accelerate the development of stem cell-derived tissues and organs for transplantation.
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CRISPR tagging used to grow neuronal cells from stem cells
A new technique using CRISPR has been developed by researchers to identify programmed stem cells that mature into neuronal cells.
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Transcription factor source for customised stem cell programming
Researchers have found a way to systematically extract various cell types from induced pluripotent stem cells and made their transcription factor source accessible for other scientists.
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Development of a physiologically relevant lung model for understanding SARS-CoV-2 infection
COVID-19 is known to infect the lungs; however, the dynamics of viral infection and replication are poorly understood. Alongside the Liverpool School of Tropical Medicine, Professor Lyle Armstrong and colleagues have been working to develop a human lung epithelium model of SARS-CoV-2 infection and replication. In this article, he describes…
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Drug Target Review – Issue 4 2020
In this journal, find articles discussing antimicrobial resistance, exploring why inhibiting the interaction between SARS-CoV-2 and neuropilin-1 could help combat COVID-19, as well as how CRISPR can be used to enhance productivity in cell line development. Also in this issue, features on engineering new biologic drugs and precision medicine.
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Mini lung organoids replicate COVID-19 pathology in a dish
Scientists developed a new culture technique for alveolospheres which they used to study how alveolar cells respond to SARS-CoV-2 infection.
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New 3D cell culture method could enable personalised cancer therapies
A team has extracted single tumour cells from existing cell lines to create 3D cell cultures that could allow for personalised cancer therapies.
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Cell line development services market to grow at 13.3 percent
Reports suggest the market growth is driven by advances in biotechnology and its applications, as well as COVID-19 research.
