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Study reveals every bowel tumour and bowel cancer cell have unique genetic fingerprints
Single-cell technology and organoids enable researchers to study cancer-specific processes...
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Stem Cells
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Rare brain disease in children: Major breakthroughs in Rasmussen’s encephalitis
Chronic focal encephalitis is a rare and devastating inflammatory brain disease, researchers have proven that the disease attacks patients using their own immune system...
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The National Institutes of Health announce Biobanking Medical Project
SMi Reports: The National Institutes of Health announce one of the most ambitious medical projects in biobanking, which will commence this spring.
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Early stimulation improves performance of bioengineered human heart cells
Researchers are now able to use induced pluripotent stem cells to form a model of human adult-like cardiac muscle...
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KIF5A gene associated with the development of ALS
An international team of researchers has identified a new gene associated with the development of amyotrophic lateral sclerosis...
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Expert view: Addressing the big challenges in cell-based assays
As the drug discovery industry takes on the complex disease states that plague our world, the need for more relevant and timely answers from cell-based assays has become a major challenge.
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Researchers discover switch that converts blood vessels to blood stem cells
A team of scientists in the UK and Italy has discovered a switch that instructs blood vessel cells to become blood stem cells during embryonic development in mice. These findings could aid research into new blood cell creation for transplants.
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3-D tissue model of developing heart could help drug safety testing
Researchers have combined biomaterials-based cell patterning and stem cell technology to make a 3D tissue model that could mimic early stage human heart development...
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Bone marrow stem cells may reverse effects of premature menopause
Young women with premature ovarian insufficiency may be able to use their own bone marrow stem cells to rejuvenate their ovaries and avoid the effects of premature menopause...
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Helpful B cells lend a hand to developing neurons
Researchers at Osaka University have identified an immune cell that promotes the growth of neuron-supporting cells in the developing mouse brain.
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Drug Target Review – Issue #1 2018
In this issue: how customised cell engineering advances immunotherapy, how insights into auto-immunity are providing new opportunities for immune-oncology, and advances in lab automation and robotics are accelerating the pace of antimicrobial therapy.
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Case Study: Characterisation of hiPSCs by Phenotypic Screening
Case study detailing a simple, highly reproducible phenotypic screen to characterise human induced pluripotent stem cells...
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Preventing exhaustion in immune cells boosts immunotherapy in mice
Research shows that preventing or reversing ‘T-cell exhaustion’ with targeted therapies could enhance the effects of immunotherapy.
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Six leading pharma firms to participate at Pharmaceutical Microbiology event in San Diego
SMi’s 2nd Annual Pharmaceutical Microbiology West Coast Conference will be taking place in San Diego, USA on the 7th - 8th June 2018.
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Scientists identify new stem cell that helps regenerate lung tissue after trauma
Researchers from the University of Pennsylvania have identified a lung stem cell that repairs the organ's gas exchange compartment, providing potential new approach to treat lung disease.
