article
Drug Target Review – Issue #4 2017
Issue 4 of Drug Target Review looks at artificial intelligence in drug discovery and features In-Depth Focuses on Screening, Hit to Lead and Informatics.
List view / Grid view
Stem Cells
news
Stem cell-derived intestine model mimics innate immune responses
A stem cell-derived in vitro model displays key small intestine characteristics including innate immune responses.
news
Scientists reverse diabetes using modified blood stem cells
Researchers have successfully reversed type 1 diabetes by infusing blood stem cells pre-treated to produce more PD-L1...
news
VEGF found to prolong survival of stem cells
A team of researchers have developed a new technology, which is promising to understand and treat ischemic diseases...
news
Charles River Laboratories presents newly expanded capabilities at Neuroscience 2017
Charles River Laboratories International, Inc. announced that its team of neuroscience drug discovery experts is presenting 27 scientific posters, both independently and collaboratively with clients, at Neuroscience 2017, the 47th annual meeting of the Society for Neuroscience (SfN).
news
Stem cells pave the way for new treatment of diabetes
A new study has shown how human stem cells can produce insulin-producing cells that in the future can be transplanted into diabetes patients...
news
Subset of stem cells identified as source for all cells in blood and immune systems
Study in nonhuman primates traces regeneration of blood and immune systems to 5 percent of transplanted blood stem cells...
whitepaper
Whitepaper: Automatic calculation of HeLa cell culture confluency
Cell confluency is a key parameter for all cell biologists as it is the beginning of all other cell culture experiment such as transfection, cell-based assays and cell culture quality control...
news
Phenogenetic map created for stem cell models of neurological diseases
Researchers have performed meta-analysis of neurological and neurodegenerative diseases and created an atlas of how cell characteristics are linked to their genotype...
news
Cell contacts in embryonic development determine cellular fate
Researchers have identified a positive feedback loop between the duration of cell-cell contacts and the specification of a cell's fate...
news
Stem cell line offers expanded potential for research and treatments
Researchers have created Expanded Potential Stem Cells that have greater potential for embryonic development than current stem cell lines...
article
EUTCD-Grade lines: an innovative approach to creating and supplying clinical hESC lines
The ever-increasing pressure to turn bench-top discoveries into new therapies has led to the re-purposing of embryonic stem cell lines, originally intended for basic research, for clinical applications...
article
Drug Target Review – Issue #3 2017
Included in this issue: The importance of industry partnerships; Calcilytics as potential novel therapeutic treatments to halt Alzheimer's disease; Accelerating neuroscience research with flow cytometry...
news
New headquarters in Scotland strengthens drug discovery research
A provider of products and services for research in stem cells, drug discovery, human tissues and 3D cell culture has opened its European headquarters in Glasgow, UK...
news
New marker could refine the process of producing hPSC-derived insulin cells
Scientists at the University of Copenhagen have identified a unique cell surface protein present on human pancreatic precursor cells providing for the first time a molecular handle to purify the cells whose fate is to become cells of the pancreas - including insulin producing cells.
