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Vitamin C effective at targeting cancer stem cells
Vitamin C is up to ten times more effective at stopping cancer cell growth than pharmaceuticals such as 2-DG, according to an article published in Oncotarget
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Stem Cells
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Targeting GAS6 in cancer, fibrosis and viral infection
The growth-arrest specific 6 (GAS6) protein has emerged in recent years as an attractive target for drug development primarily because it is the sole ligand for the AXL receptor tyrosine kinase, which plays critical roles in cancer, fibrosis, and viral infection.
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Drug Target Review – Issue #1 2017
Included in this issue: Importance of building patient trust; Vaccines & Immunology; Oncology; Assays; Biomarkers; and Antibodies...
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Nanoinjection increases survival rate of cells to 90%
How do tumours grow? And how do bacteria transform harmless substances into medical agents? When biophysicists want to understand what is happening in living cells, they have to introduce fluorescent probes or other foreign molecules. There are several ways to overcome the cell wall without causing the cell permanent harm.
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Human neurons in mouse brains are more susceptible to Alzheimer’s pathology
Cells behave differently when removed from their environments, just as cells that develop in cultures do not behave like cells in living creatures.
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How blood stem cells can be rejuvenated
Our blood stem cells generate around a thousand billion new blood cells every day. But the blood stem cells’ capacity to produce blood changes as we age. This leads to older people being more susceptible to anaemia, lowered immunity and a greater risk of developing certain kinds of blood cancer.
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Obesity can reprogram muscle stem cells
Obesity is associated with reduced muscle mass and impaired metabolism. Epigenetic changes that affect the formation of new muscle cells may be a contributing factor, according to new research from Lund University, Sweden.
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Deep Learning predicts hematopoietic stem cell development
Autonomous driving, automatic speech recognition, and the game Go: Deep Learning is generating more and more public awareness.
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Stem cell ‘marking’ study offers alternative hypothesis of cancer metastasis
Stem cells are among the most energetically activated, migratory and proliferative sub-populations of tumour cells, according to observations by scholars at the Biomedical Research Centre at the University of Salford.
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Product Hub: The growing potential of hiPS-derived beta cells
Christian Andersson, Product Development Manager at Takara Bio discusses hiPS-derived beta cells, which offer an unprecedented opportunity for diabetes research to model human physiology and ‘diseases in a dish’. Christian looks into the potential for new discoveries for diabetes and other metabolic diseases...
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Amgen and Immatics to collaborate on bispecific cancer immunotherapies
The collaboration will combine Immatics’ Xpresident target discovery and T-cell receptor (TCR) capabilities with Amgen’s validated Bispecific T-cell Engager (BiTE) technology with the aim of creating novel oncology drugs.
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ProteinSimple Milo
12 January 2017 | By ProteinSimple
Single-Cell Western system capable of analysing protein expression in ~1,000 single-cells in parallel to unlock heterogeneity...
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Immunotherapy and gene therapy combination shows promise against brain tumours
The outlook for brain tumour patients is pretty negative, with the median survival rate for patients with glioblastoma multiforme, or GBM, a mere 14.2 months.
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TSRI’s rat study shows how brain stores memories
A new study led by scientists at the Scripps Research Institute (TSRI) sheds light on how the brain stores memories.
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Mission Therapeutics appoints Colin Goddard as Chairman
Mission Therapeutics have appointed Dr Colin Goddard as non-executive Chairman, effective January 1st 2017.
