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Antibodies In-Depth Focus 2016
In this Antibodies In-depth Focus: Antibody fragment technology and avian IgY antibodies: a powerful combination; plus the challenges with antibody-based targeting of VEGF...
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Stem Cells
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Pushing the limits of protein expression with miRNAs
Biopharmaceuticals are highly complex protein drugs such as antibodies, cytokines and peptide hormones, which are used for a variety of indication areas, including immunology, neurology, metabolic diseases and cancer. These modern protein drugs may hinder progression of a disease, ease symptoms or assure – in the case of chronic diseases…
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Blood stem cells study could pave the way for leukaemia therapy
10 March 2016 | By Victoria White
Scientists are a step closer to creating blood stem cells that could reduce the need for bone marrow transplants in patients with cancer or blood disorders...
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Urine of premature babies a novel source of kidney stem cells
7 March 2016 | By Victoria White
A team, led by Professor Elena Levtchenko from KU Leuven, discovered that kidney stem cells are abundant in the urine of premature babies...
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Likely link found between Zika virus and microcephaly
4 March 2016 | By Victoria White
Working with lab-grown human stem cells, a team of researchers suspect they have discovered how the Zika virus probably causes microcephaly in foetuses...
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Scientists derive naïve pluripotent stem cells from human embryos
4 March 2016 | By Victoria White
Naïve pluripotent stem cells are one of the most flexible types of stem cell, which can develop into all human tissue other than the placenta...
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Celyad gets patent for TCR-deficient CAR T-cell method
2 March 2016 | By Victoria White
The US Patent 9,273,283 is the second patent of Celyad allogeneic intellectual property portfolio that is awarded by the USPTO...
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EMD Millipore: Reput(Ab)le – Cancer-Signaling Antibodies
1 March 2016 | By Merck KGaA
With EMD Millipore’s comprehensive portfolio of reagents and antibodies, researchers can count on dependable, high-quality solutions for analysing all the hallmarks of cancer...
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Directing a weaponised attack on cancer with Natural Killer Receptor T-Cells
23 February 2016 | By Dr Frédéric Lehmann, VP Immuno-Oncology, Celyad
Natural killer receptor T-cells have the potential to become a real game changing treatment for patients with cancer. Here, Dr Frédéric Lehmann, VP Immuno-Oncology, Celyad, discusses this new cancer fighting technology...
whitepaper
Handbook: An introduction to Antibodies and their applications, 3rd ed
A concise overview of some of the key features for the use of antibodies and immunochemical techniques in biological research...
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Studies suggest major role for Regen’s NR2F6 target in controlling key immune functions
18 February 2016 | By Victoria White
The results demonstrate that suppression of NR2F6 in T-cells results in increased expression of key immune stimulatory proteins IL-17 and IL-18...
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‘Extraordinary’ t-cell cancer therapy results generate excitement
16 February 2016 | By Victoria White
In one study, the engineered T-cells induced complete remission in 94% of patients with acute lymphoblastic leukaemia...
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Stem cells that can repair the skull and face bones
1 February 2016 | By Victoria White
Scientists have, for the first time, identified and isolated stem cells capable of skull formation and craniofacial bone repair in mice...
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CRISPR used to repair genetic mutation in retinitis pigmentosa
27 January 2016 | By Victoria White
The study marks the first time researchers have replaced a defective gene associated with a sensory disease in stem cells that were derived from a patient's tissue...
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Microptosis could present an antimicrobial drug development opportunity
20 January 2016 | By Victoria White
Researchers have described a novel pathway called microptosis where the immune system's killer cells deliver a 3-phase knockout punch that kills intracellular parasites...