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Scientists uncover how adult muscle stem cells are regulated
Researchers find that mitochondria’s shape transitions as they elongate and divide are in fact regulating the dormant state of adult muscle stem cells.
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Stem Cells
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Stem cells could repair spinal cord injuries
Researchers have identified latent stem cells that could respond to spinal cord injuries.
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Engineering cell lines for rare disease research and precision therapeutics
19 August 2022 | By Sartorius
Want to learn about the latest research and development of cell models in rare diseases? Then watch this virtual panel discussion to hear from industry experts.
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Progress towards a stem cell-based therapy for blindness
Scientists are developing an effective stem cell-based therapy to regenerate photoreceptors cells and restore sight in people with blindness.
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Application note: LlaMAbody™ camelid antibodies flyer
Single-domain antibodies (sdAb) are small, stable antibodies derived from camelids with a single monomeric variable domain.
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Handbook: Western blot
Find western blot application protocols and troubleshooting tips for detecting proteins in this handbook.
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Video: Did you know that ddPCR technology offers lower variability for viral titer determination?
Droplet Digital PCR (ddPCR) offers greater accuracy and precision in quantifying viral titer in gene therapies.
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Concerns for future gene therapy testing in laboratory mice
Researchers have found that new sickle cell disease gene therapies depend on choosing the right laboratory mice.
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New immune targets to improve survival from sepsis
In a pre-clinical study, researchers from the US set out to develop a treatment for sepsis. Here, Daniel Morales-Mantilla, Dr Robin Parihar and Dr Katherine King, from Baylor College of Medicine, describe how they utilised haematopoietic stem and progenitor cell infusion to improve the survival of mice from sepsis.
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Using cortical spheroids to study endocannabinoids and autism spectrum disorder
The endocannabinoid system may play a role in the development of autism spectrum disorder and might be key to treating people with severe forms of the condition. In this commentary, Dr Karen Litwa, Assistant Professor at East Carolina University’s Brody School of Medicine, US explores how a bioelectronic assay is…
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Infographic: Detecting Mycoplasma contamination in your cell culture with confidence
This infographic will explore Mycoplasma contamination in cell cultures and the best technologies for detection.
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Human urine-derived stem cells have robust regenerative potential
A new study provides the possibility to evaluate the capacity of telomerase-positive human urine-derived stem cells to become a wide variety of other cell types.
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Product hub: A reproducible and scalable Huntington’s disease human cell model
Senior scientist Dr Tony Oosterveen discusses bit.bio’s new ioDisease Model portfolio, including new models for Huntington’s disease to help advance in vitro research and drug discovery.
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The promise of cell therapy: scaling up a new treatment paradigm for hearing loss
Expectations are growing worldwide for discoveries that will harness the potential of cell therapy, which has already brought breakthroughs in therapeutic areas where there is an unmet need, from oncology to ophthalmology and rare disease. In this article, Dr Terri Gaskell, Chief Technology Officer at Rinri Therapeutics, explores some of…
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Whitepaper: CAR T-Cell analysis with modular antibodies using SpyTag protein ligation
Here Bio-Rad presents the generation of specific anti-CAR T-cell antibodies to show how CAR T-cell analysis benefits from our modular antibody assembly technology using SpyTag-SpyCatcher protein ligation.
