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Experimental antidepressant could also treat alcohol use disorder
A US pre-clinical study investigating the antidepressant: MAP4343, discovered it reduced alcohol intake in a mouse model of alcoholism.
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Measles virus can develop mutations that cause fatal SSPE
Japanese researchers find a new mechanism for how the measles virus can cause a rare but fatal neurological disorder: subacute sclerosing panencephalitis (SSPE).
whitepaper
Whitepaper: Oncology therapeutics discovery solutions
Streamline oncology therapeutic development with CST® recombinant monoclonal antibodies, ELISA & cellular assay kits, & custom products & services.
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Can ketamine act as an antidepressant?
Chronic pain often leads to depression, which US researchers have potentially solved using a mechanism involved with ketamine.
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Discovery of CAFs’ origin gives new direction for pancreatic cancer
US researchers discovered a type of cell involved it pancreatic cancer and sheds light on the origin of cancer-associated fibroblasts (CAFs).
webinar
Successful hit finding for PIM3 kinase inhibitors: from HTS to extended hit characterisation including Spectral Shift technology
31 January 2023 | By Eurofins Discovery Services
In this webinar, we discuss the classical HTS approach and how Eurofins Discovery capabilities can help you to quickly and efficiently, initiate your Hit-to-Lead program.
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Hypothalamus versus hippocampus: changes in the synaptic plasticity
Japanese scientists analyse the associative synaptic plasticity in the supramammillary nucleus–dentate gyrus pathways.
webinar
Using integrative biophysical approaches to understand GPCR regulation by β-arrestins
30 January 2023 | By Thermo Fisher Scientific
Watch this webinar to learn how an integrated structural biology workflow can be used to get crucial structural insights on key protein targets that are of therapeutic interest.
news
Host-cell factors involved in COVID-19 infections may predict improved treatments
Researchers have found a potential therapeutic target less vulnerable to potential drug resistance and emerging COVID-19 variants of concern.
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Combination of MRI and MSI uncover molecular secrets of Alzheimer’s
US researchers will use a unique combination of imaging techniques (MRI and MSI) to study Alzheimer’s disease on a scale that has never been done before.
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The role immunological memory plays in fighting disease
US research about immunological memory may help development of potential vaccines or immunotherapies for cancer and various inflammatory diseases.
article
2023 and beyond: revolutionising drug discovery
Drug discovery trends in 2023 will change the way we conduct science and result in entirely new, more efficient, and effective research paradigms. Through increased public-private partnerships, multidisciplinary collaboration and patient engagement in the drug discovery process, we will see new vaccines and therapies getting to the public faster and…
article
Developing state-of‑the‑art CAR T-cell therapy for cancer treatment
In this Q&A, Dr Frank Neumann speaks about Kite Pharma’s work with chimeric antigen receptor (CAR) T-cell therapy and how the company is working to progress this next‑generation modality even further to help treat cancer patients.
news
Unexpected neuronal molecule makes prostate cancer more aggressive
US researchers discover a potential therapeutic avenue through the molecule NgR2, against an aggressive form of prostate cancer.
news
New treatment for MS using artificial nerve fibres
Danish researchers undertake a new project that aims to find new forms of treatment for diseases such as MS, which breaks down myelin and nerve fibres, by developing new, artificial nerve fibres
