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New insights on the structural biology of medical cannabis
French researchers underwent a structural study showing that THC cannabinoids inhibit a human enzyme called autotaxin.
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Targets
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Could drinking green tea, red wine and beer prevent Alzheimer’s?
In this article, Drug Target Review’s Izzy Wood reviews some of the latest Alzheimer's disease research, highlighting the progress that has been made toward new, more unique therapeutic strategies against Alzheimer’s.
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Humanised mouse model identifies the best match for organ donor
US researchers have developed a mouse model that holds promise in identifying the best organ donor and showing early signs of transplant rejection.
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Memory loss could be solved using an asthma drug
Dutch researchers, using optogenetic approaches and an asthma drug, discovered that memory loss from sleep deprivation can be retrieved.
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Novel protein coordinates melanin production
Japanese researchers reported that a key transcription factor “Nrf3” regulates the process of melanin production in mouse and human cells.
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Application note: Kinetic quantification cell proliferation in live cells
Cell proliferation assays are a cornerstone of cancer therapeutic, developmental biology, and drug safety research.
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Cell organisation determined by new mathematical framework
US scientists, using high-resolution imaging, debuted a new way to see cell organisation and rich variation in cell shape
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Executive summary: Scale-up strategies for late-stage cell therapies
Discover how Catalent can help you achieve efficiencies and develop a robust, reproducible manufacturing plan for late-stage and commercial launch.
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Synthetic tissue helps restore and repair erectile function in animal models
Chinese scientists have developed a synthetic tissue that repairs penile injuries and restores normal erectile function in pigs.
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A promising oral drug delivery platform could replace injections with pills
The researchers explored the possibility of using the probiotic bacteria Lactobacillus reuteri as a novel oral drug delivery platform to treat rheumatoid arthritis in an animal model.
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50 year old blood pressure drug offers alternative treatment for PTSD
US scientists offer a new purpose for the blood pressure drug clonidine as a treatment to reduce the affects of PTSD.
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Poster: Antibodies for microglial activation states
Development of novel rabbit monoclonal antibodies to characterise microglial activation states in murine models of Alzheimer’s disease.
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Protein Grb10 offers a potential new approach for treating obesity
The researchers found that the protein Grb10 promotes leptin activity in the brain, opening the possibility of developing Grb10-based new approaches to treat obesity.
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Novel cancer vaccine simultaneously kills and prevents brain cancer
US researchers develop a dual-action cell therapy engineered to eliminate established tumours and train the immune system to eradicate primary tumour and prevent cancer’s recurrence.
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Application note: Dynamic quantification of cell migration in real time
Discover the Incucyte® Scratch Wound Analysis Software Module for automated image-based measurements of cell migration in vitro, using label-free analysis.
