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Findings on pancreatic cancer could improve immunotherapies
Researchers have revealed the immune landscape and microbiome of pancreatic cysts as they progress to pancreatic cancer, providing targets for immunotherapy.
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The 3D structure of a twinkle protein has been developed for the first time
Researchers have developed a 3D structure that allows them to see how and where disease mutations on the twinkle protein can lead to mitochondrial diseases.
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Scientists generate a mouse embryo model that develops neural tubes
The new mouse embryo model system promises to spur research into developmental health and disease.
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RASA2 gene make T cells more resilient
New study finds that using CRISPR to block RASA2 gene makes T cells more resilient against cancer.
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Researchers find CD39 inhibition could be an effective strategy for immunotherapy
Scientists have discovered adenosine could inhibit CD39, a molecule that suppresses the immune system.
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New method by which T cells can react to lower doses of antigens
Researchers have discovered a way to ignite T cells, potentially increasing the scope and success of T cell-based immunotherapy.
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Combining immunotherapy and virotherapy shows promise for treatment-resistant cancers
The study describes how oncolytic virotherapy can work with existing immunotherapy techniques, boosting the immune capacity to effectively target and destroy cancer cells.
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Decoding cancer and inflammation: identifying selective inhibitors of SH2 domains
31 August 2022 | By Eurofins Discovery
Watch our on-demand webinar where our expert speaker will explore the possibilities for designing selective small molecules targeting the SH2 domains of STAT proteins plus more.
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A new strategy to overcome tumour-induced immunosuppression
Researchers have found that blocking key enzymes could boost anti-cancer T cell responses and resistance to immunosuppression.
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New findings could lead to a vaccine that can offer protection against emerging COVID-19 variants
Scientists have discovered antibodies that are effective against many different COVID-19 variants.
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Application note: Quantifying T Cell response in 3D tumour spheroids
Application note: Quantifying T Cell response in 3D tumour spheroids using advanced flow cytometry workflows.
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Universal flu vaccine protects against influenza A and B viruses
Vaccinating mice with this universal flu candidate induced broad neuraminidase inhibition, M2 ectodomain specific antibodies and T cell immune responses.
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How to tackle the immense challenge of delivering vaccines
Researchers have developed a safe and versatile platform to increase the thermal stability of vaccines and improve their transportability.
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New generation of COVID-19 vaccines show promising results
Researchers have designed a COVID-19 vaccine to be less sensitive to mutations and equipped for future strains.
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How T cells migrate from the tissue to the lymph nodes
Scientists have found that unconventional T cells migrate from tissue into the lymph nodes and influence immune responses there.
