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14 April 2022 | By Eurofins Discovery Services
Watch this free on-demand webinar to understand how to rapidly identify selective, specific, potent and tractable hit series with appropriate ADME characteristics to speed up hit-to-lead.
The antigen-based vaccine has the potential to induce sterilising immunity to old and new SARS-CoV-2 variants by preventing infection by stopping viral replication and transmission through the inhibition of cellular virus entry.
Researchers have developed a novel substance that disables a protein in the cell skeleton, leading to cell death. In this way, substances of this type can prevent the growth of tumours.
Pfizer has announced its acquisition of ReViral to advance disease research and development with a complementary strategy to help improve patient outcomes through treatment for respiratory syncytial virus infections and prevent illness through vaccination.
Pre-clinical research from VBI Vaccines has demonstrated an encouraging ability to boost and broaden the immune response against the coronavirus Beta variant.
Scientists have developed a delivery method that enhances treatment by adding CAR T cells and specialising signalling proteins to a hydrogel that is injected next to a tumour.
New research has shown iron-like compound holds promise for treating patients with glioblastoma, an aggressive brain cancer.
Looking at disease through a patient’s memory B cells can reveal vulnerabilities within pathogens. In this article, Dr Purnanand Sarma, President and Chief Executive Officer of Immunome, explores how advancements in memory B-cell antibody-based treatments will improve our understanding of how these cells can aid in fighting cancer and other diseases.
A monoclonal antibody (mAb) developed by IGM Biosciences to combat COVID-19 has shown success in pre-clinical studies and has now moved into Phase I trials. In this Q&A, Dr Chris Takimoto, Chief Medical Officer at IGM Biosciences, explains how this biotherapeutic works to prevent and treat SARS-CoV-2 infection.
Scientists have found that molecules produced by cells in response to stress may be indicators of various diseases.
CAR T cells have shown incredible promise in the clinic, but there is still room for advancement. One avenue for improvement is through modification of the CAR design. However, given the number of exchangeable domains, testing all variations can present a hurdle. In this article, Dr Sarwish Rafiq, Assistant Professor in…
A new study from the University of Michigan Rogel Cancer Center, US has revealed that a cytokine and a fatty acid can work together to trigger ferroptosis. Here, Dr Weiping Zou, the lead researcher from the study, outlines how this process could be used to target cancer cells and enhance immunotherapies.
Researchers have been using brain organoids to understand how a mutated gene affects the brain at its very early stage of development.
A new study by University of Texas Health Science Center at San Antonio has found that boosting liver mRNAs in obese mice reduces appetite and body weight.
Almirall and University of Dundee announce a collaboration to develop a novel treatment to fully control itch in skin diseases and achieve a prolonged and profound therapeutic effect for patients.
