news
Antibodies that can neutralise SARS-CoV-2 Omicron variant identified
A study has revealed four classes of antibodies that can neutralise Omicron by targeting one of four areas of the spike protein present in SARS-CoV-2 variants.
List view / Grid view
Targets
news
Antibody drug target identified for influenza viruses
Researchers have found a small subset of antibodies that target a site at the base of the influenza virus hemagglutinin protein.
news
Cancer-promoting gene a potential target for pulmonary hypertension
The new study identified PDZ-binding kinase (PBK) as a promising target for pulmonary hypertension and assessed two PBK inhibitors.
news
Brain recordings could improve deep brain stimulation therapy for OCD
Scientists captured more than 1,000 hours of brain recordings from obsessive compulsive disorder (OCD) patients and uncovered candidate neurological signatures.
news
Nanotechnology boosts immune response at tumour site in mice
The new nanotechnology left six of 10 mice with lymphoma tumour-free and was effective in melanoma when combined with existing drugs.
news
Experimental gel promotes arteriovenous fistula (AVF) formation in rodents
The self-assembling, nanomatrix gel may represent the first effective therapy to promote healthy arteriovenous fistula (AVF) maturation in kidney disease patients.
whitepaper
Product hub: Stay at the forefront of neuroscience research
Read about our comprehensive portfolio of rigorously developed kits harnessing the ultrasensitive Single Molecule Counting (SMC™) technology.
news
Common antioxidant reduces osteoarthritis markers in knee cartilage cells
Gallic acid was found to decrease arthritis inflammation markers and improve the production of desired proteins in arthritic knee cells.
news
Mechanism that causes ALS nerve destruction unveiled for first time
The study reveals the biological mechanism that causes nerve destruction in amyotrophic lateral sclerosis (ALS), potentially leading to treatments that reverse the disease.
news
Researchers investigate gene network to identify “cancer driver genes”
The new study looked at the network of gene-gene interactions associated with cancer onset and progression to identify therapeutic targets.
article
Drug Target Review – Issue 4 2021
This issue includes articles that discuss the development of long-term 3D tissue cultures from human biopsy samples, the application of flow cytometry in drug discovery and automation for upstream processing in a biologics manufacturing environment. Also included are features on informatics, proteomics and CRISPR.
news
Transformable nanoparticles promise advances in tumour treatments
A new study provides an in-depth review on the designs and applications of morphology-transformable nanoparticles to improve cancer therapies.
news
Three RNA-expression states may reveal cancer drug susceptibility
Scientists identified three prototypical RNA-expression states and revealed differences in their susceptibility to a variety of cancer drugs.
news
Scientists discover novel B cell that tempers autoimmunity
Infusions of purified IL-27 regulatory B cells (I27-Bregs) reduced symptoms in mouse models of multiple sclerosis and autoimmune uveitis.
news
Experimental enzyme treatment protects mice from lethal anthrax infection
All mice infected with anthrax spores were completely protected after treatment with a pegylated enzyme known as PEG-CapD-CPS334C.
