Non-invasive optical method could provide insight into brain diseases
A non-invasive, label-free optical method can produce high-resolution imaging of cellular brain diseases in vivo.
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High-quality, rapid technique developed for imaging in vivo
A US team has designed a high-quality, high-speed imaging system that could lead to new understandings of complex tissue specimens.
New spray shown to help heal heart attack damage in rats
A team have developed a minimally invasive exosome spray that helped repair rat hearts after myocardial infarction.
Metal-based molecule could inhibit build-up of Alzheimer’s peptides
UK researchers have created a metal-based molecule that inhibits the build-up of Alzheimer’s-associated peptide, amyloid-β, in lab tests.
Microcrystal electron diffraction could advance drug development
UK researchers have shown how microcrystal electron diffraction (MicroED) could obtain the structures of potential pharmaceuticals.
Prenatal editing halts progression of Hurler syndrome in pre-clinical model
US researchers used an AAV9 vector to edit a single base mutation in a prenatal mouse model, halting progression of Hurler syndrome.
Therapeutic target discovery could improve breast cancer treatments
Research by a team in Canada reveals a promising therapeutic target to counter HER2-positive breast cancer.
“Woman-controlled, on-demand” contraceptive product developed in US
US researchers have developed an antisperm monoclonal antibody that could become a safe and effective birth control method.
Screening method finds potential drugs to repurpose against COVID-19
Researchers have identified 38 drugs that could be repurposed to treat COVID-19 through a strategy involving virtual screening and cell-based assays.
Defective proteins found to be potential targets for Alzheimer’s treatments
US researchers have identified potential new treatment targets for Alzheimer’s disease, as well as existing drugs that could be used against these targets.
Newly designed tumour vaccine could prevent cancer recurrence
Scientists have used nanotechnology to develop personalised tumour vaccines which prevented cancer recurrence and metastasis challenges in mouse models.
Artificial intelligence method generates synthetic active ingredients
A team in Switzerland have demonstrated how artificial intelligence could be used in the search for new pharmaceutical agents.
Anticoagulant drug a possible strategy to treat COVID-19 variants
Researchers in Australia have discovered a new site on the COVID-19 Spike protein that could be targeted by an anticoagulant drug.
Metabolic pathway could potentially enhance vaccine effectiveness
A metabolic control pathway that regulates T follicular helper cells could enhance vaccine effectiveness, including those that protect against COVID-19.
Protein activation discovery could widen access to cancer immunotherapy
The activation of the protein p53 was shown to boost immune responses against cancer tumours in mice in a new study, potentially widening access to immunotherapy.
