New 3D lung-on-a-chip model enables study of respiratory diseases
Scientists have developed a 3D lung-on-a-chip model of the distal lung and alveolar structures, enabling the study of COVID-19.
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Small-molecule cocktail could improve use of stem cells in treatments
Researchers have shown that Chroman 1, Emricasan and trans-ISRIB, in combination with polyamines, are effective at protecting induced pluripotent stem cells from stress.
UK to host summit with CEPI to accelerate vaccine development
A summit will be held between the UK and CEPI to raise funds for vaccine research and development in a bid to avert future pandemics.
New imaging method visualises respiratory activity of cell models
Researchers have created a new imaging technique called electrochemiluminescence to visualise multiple spheroids with a single shot.
CRISPR reveals genes involved in zebrafish spinal cord regeneration
A CRISPR-Cas9 method has been used to identify which genes play a role in repairing zebrafish spinal cord injuries.
Avocado compound targets enzyme critical to leukaemia cell growth
The fat molecule avocatin B, found in avocados, was shown to inhibit VLCAD, an enzyme vital for leukaemia cell metabolism.
Novel nanopore platform developed to sequence DNA
Scientists have created a new nanopore sequencing platform that can detect the presence of the nucleobases of DNA.
UK Government to fund £37 million into genomics projects
UK Health Secretary Matt Hancock has announced £37 million of funding for genomics and data projects to support the life sciences sector.
Purified exosomal product heals ischemic wounds in pre-clinical models
Researchers have found that ischemic wounds in pre-clinical models which were treated with a purified exosomal product were healed.
Raman spectroscopy platform developed to characterise IDPs
Optical tweezers-coupled Raman spectroscopy has been used to reveal the structure of alpha-synuclein, an IDP linked to Parkinson's disease.
Gene changes caused by Spike protein could explain long COVID
Scientists have shown that the SARS-CoV-2 Spike protein can initiate gene expression changes, potentially explaining long COVID symptoms.
New 3D organoid model of pancreas developed from human stem cells
Researchers have developed the first 3D organoid models of the pancreas that includes both the acinar and ductal structures.
Antibody cocktail shown to neutralise SARS-CoV-2 variants of concern
A new antibody cocktail made from three mAbs neutralised several SARS-CoV-2 variants in pre-clinical studies.
First comprehensive single-cell atlas of human teeth compiled
Using single-cell sequencing technology, researchers have gained insight into the interactions of dental pulp and periodontal cells of teeth.
Sanguinarine shows promise against triple-negative breast cancer
A new study in cell cultures has shown that the sanguinarine plant compound could be used to treat people with triple-negative breast cancer.
