SARS-CoV-2 infection induces polyfunctional antibodies, study finds 22 April 2021 | By Victoria Rees (Drug Target Review) Using newly developed assays, researchers have characterised the antibody response of individuals infected with SARS-CoV-2.
Stem cell therapy repairs damage from dementia in mouse brains 22 April 2021 | By Victoria Rees (Drug Target Review) Researchers have developed a stem cell therapy that could treat the damage caused by dementia by launching a repair response.
Drug development platform could provide targeted antimicrobials 21 April 2021 | By Victoria Rees (Drug Target Review) Researchers have developed a platform named FAST to produce antibiotics that specifically target just the bacteria of interest.
Label-free technique used to visualise lipid content in mouse livers 21 April 2021 | By Victoria Rees (Drug Target Review) Researchers have successfully used label-free near-infrared hyperspectral imaging for mouse livers, which could aid in the diagnosis of NAFLD.
Team develops cerebral organoid system to screen for CJD drugs 20 April 2021 | By Victoria Rees (Drug Target Review) Researchers have developed their previously created brain organoid to test for potential drugs against Creutzfeldt-Jakob disease (CJD).
New software could enable the design of DNA robots for drug delivery 20 April 2021 | By Victoria Rees (Drug Target Review) Researchers have developed software that can design complex DNA nanodevices which could be used to deliver medicine while in the body.
Algorithm created to analyse large single-cell sequencing datasets 20 April 2021 | By Victoria Rees (Drug Target Review) An algorithm which continuously processes new data has been developed to allow researchers to access and analyse single-cell sequencing information.
Novel COVID-19 vaccine could offer broad protection from coronaviruses 20 April 2021 | By Victoria Rees (Drug Target Review) A new COVID-19 vaccine could provide protection from severe infection from a range of coronaviruses, studies in pigs have shown.
Scientists develop new CRISPR-based tool to control epigenome 19 April 2021 | By Victoria Rees (Drug Target Review) Researchers have used CRISPR to create a new technology that can switch off almost any gene in cells, called CRISPRoff.
MK-4482 antiviral effective against SARS-CoV-2 in hamster study 19 April 2021 | By Victoria Rees (Drug Target Review) The drug MK-4482 decreased viral levels in the lungs of hamsters treated for SARS-CoV-2 infection, researchers have shown.
Assay developed to detect cathepsin B in blood samples 19 April 2021 | By Victoria Rees (Drug Target Review) Scientists have created an assay to detect the protein cathepsin B in blood, a biomarker for a range of diseases.
Researchers increase frame rate of high-speed atomic force microscopy 19 April 2021 | By Victoria Rees (Drug Target Review) By increasing the frame rate of atomic force microscopy to 30 frames per second, scientists found the technique was faster and less invasive.
Brain organoids reveal mechanisms of virus-induced microcephaly 16 April 2021 | By Victoria Rees (Drug Target Review) Researchers have shown how different viruses such as HSV-1 and Zika can lead to microcephaly using brain organoids.
Machine learning method to design better antibody drugs developed 16 April 2021 | By Victoria Rees (Drug Target Review) Researchers have developed an artificial intelligence to identify the best potential antibody drug from groups of up to a few thousand.
Scientists generate human-monkey chimeric embryos 16 April 2021 | By Victoria Rees (Drug Target Review) An international collaboration has led to the development of monkey embryos able to grow with injected human stem cells.
