Structure of protein that triggers neurodegeneration isolated and analysed
Using X-ray crystallography and cryo-electron microscopy, researchers have elucidated the structure of the SARM1 protein, a target for neurodegeneration.
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Using X-ray crystallography and cryo-electron microscopy, researchers have elucidated the structure of the SARM1 protein, a target for neurodegeneration.
Researchers have discovered the the compound triptonide is safe, effective and reversible as a male contraceptive in animal models.
A team has used two viruses to administer specific tumour components in mice with cancer to stimulate their immune system.
Using high-throughput screening techniques, researchers have identified two families of active substances that block SARS-CoV-2 replication.
A team has created a biosynthetic pathway for E. coli that allows the bacteria to produce a common arthritis drug.
A new nanoparticle-based vaccine has demonstrated success in ferret models of COVID-19, inducing strong neutralising antibodies against SARS-CoV-2.
In pre-clinical studies, a novel treatment decreased plaque formation, meaning it could be used to prevent Alzheimer's disease.
A novel in silico approach applied to drug screening has revealed three potential candidates that may interact with multiple proteins of SARS‐CoV‐2.
A new study has suggested that asymptomatic individuals with COVID-19 mount an efficient T-cell response that protects the host.
A team of researchers have used microscopy techniques to monitor DNA degradation and anticancer drug release from nanostructures.
Researchers have developed a new screening technique called biological activity-based modelling to identify drug candidates.
Researchers have shown that administering a urinary tract infection vaccine directly to the bladders of mice helped them to effectively fight bacteria.
A new coarse-grained model of the complete SARS-CoV-2 virion has revealed potential new ways to combat the coronavirus.
A team has demonstrated that their bioinformatics approach, PlasmidHawk, can analyse DNA sequences to identify the source of engineered plasmids.
Researchers have found that the spasmolytic drug hymecromone can suppress astrocyte inflammatory responses, meaning it could be used to combat Alzheimer's disease.