First patient-derived organoid model for cervical cancer developed
Novel organoid models of cervical cancer and a healthy human cervix have been developed to study the condition and its progression.
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Novel organoid models of cervical cancer and a healthy human cervix have been developed to study the condition and its progression.
A team has demonstrated in mouse models that a self-assembling nanofibre material could limit the damage caused by cytokines in inflammatory diseases.
Researchers have used fragment screening alongside computational docking to reveal 20 hit antiviral compounds against SARS-CoV-2.
Scientists have discovered that manipulating residues enables precision during the antibiotic biosynthesis assembly line.
Delivering Txnip to mice with retinitis pigmentosa was an effective treatment, making this approach a potential gene therapy for the disease.
Induced pluripotent stem cells (iPSC) intestinal organoids have been created to duplicate SARS-CoV-2, enabling drug testing.
Researchers say that inhibiting NLRP3 with Dapansutrile could be an effective strategy to prevent melanoma tumour growth.
Scientists have visualised the spatial and temporal distribution of neural stem cell activation in zebrafish models.
Scientists have shown that culturing cells with a modified serum could allow drugs to be screened for toxicity earlier during research.
Researchers have shown that an mRNA delivery system can be used to produce the BDNF protein in rats to protect neurons from ischemia.
Scientists have developed PF74-like small molecules able to target the HIV-1 capsid protein, identifying four potent compounds.
Using cryo-electron microscopy, researchers have shown that the Spike (S) protein on cells exposed to the AstraZeneca vaccine is highly similar to the SARS-CoV-2 S protein.
Researchers have created a new single-cell transcriptomics approach that cryopreserves cells, limiting the stress they are put under.
Studying the mouse gene Ophn1, researchers have found its removal causes stressed behaviours, also identifying three ways to reverse this effect.
A model of the SARS-CoV-2 Spike protein surface has uncovered vulnerabilities that researchers say could inform the development of COVID-19 vaccines.