Vaccine strategy developed to fight urinary tract infections
Researchers have shown that administering a urinary tract infection vaccine directly to the bladders of mice helped them to effectively fight bacteria.
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SARS-CoV-2 model shows Spike protein co-operation
A new coarse-grained model of the complete SARS-CoV-2 virion has revealed potential new ways to combat the coronavirus.
New bioinformatics tool accurately tracks synthetic DNA
A team has demonstrated that their bioinformatics approach, PlasmidHawk, can analyse DNA sequences to identify the source of engineered plasmids.
Hymecromone can suppress neuroinflammation in astrocytes, study shows
Researchers have found that the spasmolytic drug hymecromone can suppress astrocyte inflammatory responses, meaning it could be used to combat Alzheimer's disease.
Computational method used to quantify tRNAs in any organism
Researchers have developed a new technique called mim-tRNAseq to measure, map and analyse tRNAs in cells, providing insight into disease.
Scientists uncover structural biology details of SARS-CoV-2 infection
Researchers have used computer simulations to model how the SARS-CoV-2 fusion peptide interacts with and penetrates the cell membrane.
Drugs with potential to stop plaque build-up in arteries identified
A new compound can inhibit the build-up of plaque in arteries and prevent atherosclerosis, researchers have shown.
High-throughput screening market set to be worth $26.4bn by 2025
According to a new report, the high-throughput screening market will increase at a CAGR of 11.5 percent from 2020 to 2025.
New fluorescence imaging method enables live RNA visualisation
A fluorescence imaging technique has allowed scientists to observe RNA in real time using single-molecule localisation microscopy.
Blocking Treg pathway sensitises mice to immunotherapy
Researchers have shown that inhibiting Treg activation in tumours can provide effective immune responses without autoimmune toxicity.
Nanobodies could help CRISPR turn genes on and off
Researchers have used nanobodies to act as an assistant to CRISPR, bringing in effectors to turn specific genes on and off.
Lung and brain organoids respond differently to SARS-CoV-2 infection in lab
Researchers have developed stem cell-derived organoids to reveal how SARS-CoV-2 interacts with lung and brain cells differently.
Behavioural screen in C. elegans reveals Parkinson’s drug candidates
Researchers have developed a workflow to study the behaviour of C. elegans in a high-throughput screen to identify Parkinson's disease drugs.
Over 87,000 papers published on coronavirus since start of pandemic
Between January and October 2020, scientists globally have published more than 87,000 papers about the coronavirus.
Neuron damage from ALS reversed with new compound
Scientists have developed a compound that stops the degeneration of upper motor neurons, a contributor to amyotrophic lateral sclerosis (ALS).
