Compound from Inula viscosa plant could treat primary amoebic meningoencephalitis
Researchers have isolated a compound from I. viscosa that kills the "brain-eating" amoebae from primary amoebic meningoencephalitis (PAM).
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Novel nanobody combinations protect cells from SARS-CoV-2 in vitro
By combining nanobodies targeting different regions of the SARS-CoV-2 Spike protein, researchers were able to protect cells from infection.
New probes shine a light on the role of four-stranded DNA in human cells
A better understanding of the role of four-stranded DNA (G-quadruplex) could enhance cancer therapeutics, said the developers of the probes.
New inhaled therapy could treat deadly impacts of asthma
Scientists have developed an inhaled treatment for asthma that prevents excess mucus from building up in mice.
Nanoparticle vaccine could protect against multiple coronaviruses
A new protein-based nanoparticle vaccine protected mice against a variety of coronaviruses, researchers have shown.
Hydrogen sulphide could help to treat Alzheimer’s disease
Tests in Alzheimer's disease mouse models have shown that hydrogen sulphide can improve cognitive and motor function by 50 percent.
SARS-CoV-2 infects CNS and damages brain tissue, study shows
Researchers have shown in cells and models that the central nervous system and neurons can become a target of SARS-CoV-2 infection.
Study reveals novel targets for treating atopic dermatitis
Understanding how Staphylococcus aureus bacteria colonises skin affected by atopic dermatitis could lead to new treatments that help prevent the spread of antibiotic resistance, say scientists.
Microbiome may influence severity of COVID-19, researchers say
A study has revealed that the microbiome could impact COVID-19 severity and may be implicated in persisting inflammatory symptoms.
Novel human alveolar tissue model could help COVID-19 drug development
Researchers will use the in vitro model to study how respiratory viruses, like SARS-CoV-2, cause Acute Respiratory Distress Syndrome (ARDS) and develop potential interventions.
Revealed structure of diarrhoea virus could aid in vaccine development
Using cryo-electron microscopy, researchers have observed the structure of a diarrhoea enteric adenovirus to see how it can survive the stomach.
Immune cells discovered in lungs improve flu defence, study shows
A team has found immune cells in the lungs after infection from the flu, which protected mice against reinfection from a different strain.
SARS-CoV-2 introduced to UK more than 1,000 times before March, says genomic analysis
Researchers show that genomic tracking can be used to trace individual virus transmission lineages and could therefore be adopted for future pandemics.
Study shows how to improve cancer treatment with anti-OX40 antibodies
New insights into the mechanisms of anti-OX40 antibodies could enable their therapeutic activity to be manipulated to treat different tumours.
Atomic force microscopy reveals structure of ribosome stalk proteins
Researchers have used force atomic microscopy to show the structural dynamics at ribosome stalk proteins when building new proteins.