Oral drug blocks SARS-CoV-2 transmission in ferrets, researchers find
A team has found that their drug Molnupiravir (MK-4482/EIDD-2801) acts as an antiviral against SARS-CoV-2 in pre-clinical studies.
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Microscopy reveals four classes of SARS-CoV-2 neutralising antibodies
Researchers show that neutralising antibodies targeting the SARS-CoV-2 Spike protein have four distinct structures.
New insulin molecule can self-regulate blood sugar in rats
Researchers have developed a novel insulin molecule that responds to glucose levels in the blood sugar of rats, which they say could help patients with type 1 diabetes.
A novel CAR T-cell therapy for type 1 diabetes
Researchers show how genetically engineered five-module chimeric antigen receptor (5MCAR) T cells can be directed to destroy T cells causing autoimmune diseases.
Researchers provide new insights into SARS-CoV-2 lung pathology
The new study shows how SARS-CoV-2 significantly remodels cellular processes in just an hour and identifies potential drug targets and therapeutics for COVID-19.
CRISPR tagging used to grow neuronal cells from stem cells
A new technique using CRISPR has been developed by researchers to identify programmed stem cells that mature into neuronal cells.
Novel peptide therapy improves COVID-19 survival by LEAPS and bounds in mice
Researchers report that their LEAPS COV-19 peptides significantly improved survival in a murine model of COVID-19.
Mitochondrial protein revealed as target for cardiovascular disease
According to new research, the protein ALDH4A1 is a possible therapeutic target and diagnostic biomarker for cardiovascular disease.
New virus-like probes could make COVID-19 tests more accurate and reliable
The novel probes, known as positive controls, could make it easier to validate rapid, point-of-care diagnostic tests for COVID-19 across the globe.
Researchers identify a novel tau aggregation control mechanism
According to researchers, the more small tau protein variants expressed by neurons, the slower neurofibrillary tangles form.
Drug target to tackle COVID-19 inflammatory processes identified
Researchers have shown that the presence of the inflammasome mediated by NLRP3 is a marker and drug target for COVID-19-related cytokine storms.
Cancer-killing virus could improve precision medicine
A new cancer-killing virus called CF33 has shown success in pre-clinical trials, helping the immune system to eradicate tumours.
Researchers discover how SARS-CoV-2 reaches the brain
A new study has identified the mechanisms through which the SARS-CoV-2 virus enters the brain and how the immune system responds once it does.
Transcription factor source for customised stem cell programming
Researchers have found a way to systematically extract various cell types from induced pluripotent stem cells and made their transcription factor source accessible for other scientists.
Breakthrough in AI protein structure and folding prediction
An artificial intelligence (AI) system called AlphaFold has been developed to effectively predict protein structures and folding.