How successive mRNA vaccines shape T-cell memory
A new study shows that changes in clonal dominance characterises T-cell memory against multiple COVID-19 variants following mRNA vaccinations.
List view / Grid view
News
New insights into viral-related myocarditis
Understanding heart changes at the molecular level during early infection with adenovirus could enable identification of those at higher risk of arrhythmia.
How fusion proteins drive paediatric cancer
Researchers discover that fusion proteins and a gene regulatory protein complex interact through disordered domains.
Serum biomarkers for COVID-19 identified
Proteins regulating plasminogen-plasmin levels can be used to identify patients at risk of progressing to a severe stage of COVID-19.
New algorithm identifies high-risk precancerous lesions
Researchers have developed an algorithm which could improve diagnostics of ovarian high-grade serous carcinoma.
RAD51 prevents DNA re-replication
Researchers find that the RAD51 protein prevents genomic duplications that could arise from reactivated origins.
Brain organoids: essential ethical investigation
The potential for brain organoids to develop consciousness is a key issue in neuroscience, which has prompted new ethical considerations.
Identification of antibodies to target the NA globular head domain
The study's findings could be applied to the development of new vaccine and therapeutic strategies for influenza.
Recurrent urinary tract infections: potential cause discovered
Researchers find that an overgrowth of nerve cells in the bladder could cause rUTIs, which may offer new approaches to manage symptoms.
Potential new treatment options for KSHV-associated cancers
Treatment with Palbociclib and a compound targeting CAD increased survival to 100 percent for selected lymphoma cell lines.
Defining the senescence profile of colon fibroblasts
Researchers have generated a SASP atlas of human colon fibroblasts and assessed the resulting transcriptome.
Insights into the toxicological effects of nanoparticles
Researchers have developed a system that enabled quantitative assessment of cytotoxicity of SiNPs in human hepatoma cells.
Combatting osteoarthritis with cartilage replacement therapy
Limb bud progenitor cells efficiently generated new cartilage in osteoarthritis patients, which could lead to cartilage replacement therapy.
Novel tool to rapidly diagnose sarcoidosis
A highly specific blood test can differentiate between patients with sarcoidosis and other respiratory conditions, like TB or lung cancer.
Potential for targeted therapies based on the gigaxonin pathway
Researchers have discovered that higher expression of gigaxonin suppresses aggressive growth of human head and neck cancer cells.