Robot researcher discovers new highly active catalyst
The autonomous robot scientist can independently perform experimental procedures and makes its own decisions about which tests to perform.
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Neurological complications of COVID-19
Researchers report COVID-19 can cause a range of severe neurological symptoms, which may be the main presentation of COVID-19 in some patients.
Developing a nanoparticle-delivered gene therapy for blinding eye disease
Ophthalmology and engineering combine in a novel nanoparticle-delivered gene therapy approach to treating wet age-related macular degeneration.
Genomics England launches next-generation research platform
The genomic research platform will initially be used to help fast-track COVID-19 drug research and development, before being leveraged against other diseases, such as cancer.
Novel vitamin K analogue eliminates seizure activity in epileptic mouse models
The vitamin K-based drug has a unique structure which researchers believe makes it effective in controlling even medication-resistant seizures.
Novel class of non-addictive analgesics demonstrate safety in animals
To overcome the issues of current analgesics, researchers reveal a new class of non-narcotic pipeline drugs based on acetaminophen.
Macaques develop short-term immunity to SARS-CoV-2
Researchers experimenting on macaques reveal they were protected against reinfection up to a month after the initial exposure to SARS-CoV-2.
Protective antibodies identified for rare polio-like disease in children
Researchers isolated monoclonal antibodies from children who has survived infection by EV-D68, the virus linked to acute flaccid myelitis (AFM). These antibodies protected mice against infection.
Study identifies eight novel coronavirus replication terminators
Scientists reveal eight new molecules, five of which are already US FDA-approved, that can block the polymerase reaction SARS-CoV-2 uses to replicate its genome.
Novel targeting peptide shows promise against COVID-19 cytokine storm
Experimental peptide combination TAT CARMIL1 reduced collagen degradation as a result of cytokine storm in ex vivo study.
Experimental CAR T therapy targets solid tumour cancer cells
Scientists have developed a novel chimeric antigen receptor (CAR) T-cell therapy to target a variety of human and murine solid-tumour cancer cells.
Experimental formulation could be future for fast-acting insulin
The novel formulation hit peak activity at nine minutes, less than half the time taken for a commercially available formulation.
Researchers reveal how a key human anti-HIV antibody prevents infection
The team used cryogenic electron microscopy (cryo-EM) to show how the 10E8 antibody interacts with the HIV’s fusion protein to neutralise the virus.
Approach to produce antibiotic compounds from actinobacteria developed
Researchers have created a method to promote the production of new antibiotic or antiparasitic compounds from the genomes of actinobacteria.
Study reveals how SARS-CoV-2 rewires human proteins for replication
A team of researchers has analysed how SARS-CoV-2 hijacks the proteins in its host cells to aid replication and infect nearby cells.