Researchers reveal cryo-EM structure of remdesivir bound to SARS-CoV-2
A group of researchers has used cryo-EM to discover the structure of the remdesivir-bound RNA complex of SARS-CoV-2 and explain how the drug inhibits COVID-19 viral replication.
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Tregs produced by mesenchymal stromal cells with novel technique
By culturing blood cells with mesenchymal stromal cells (MSCs), researchers induced the production of cells with the same functionality as Tregs.
Researchers reveal structure of mega-enzymes from bacteria and fungi
Researchers have uncovered the structure of nonribosomal peptide synthetases (NRPSs), an important ingredient in drug production.
Researchers suggest COVID-19 therapeutics needed to target blood vessel leakage
According to researchers, ACE2 receptors disappear from lung cells during COVID-19, allowing small blood vessels to leak at the site of infection, presenting a new drug target.
Three new assays to test COVID-19 antivirals developed
A series of three new assays to screen for drug compounds or proteins that combat the COVID-19 coronavirus has been developed.
Collaboration to identify novel COVID-19 drug targets announced
Bringing together protein science, drug discovery experience and innovative technology, a new collaboration aims to identify novel drug targets for COVID-19.
Silicates from soil aid in triggering blood clotting, reveal researchers
A new study has revealed that the presence of soil in wounds helps to activate a blood protein known as coagulation Factor XII, leading to clotting.
Antibodies developed from llama show promise in fighting COVID-19
Engineering antibodies found in a llama, researchers have developed a potential COVID-19 therapy which they say can neutralise SARS-CoV-2.
Software developed by researchers accelerates analysis of lipids
A novel software made by scientists can be used for the analysis of specific lipid groups and lipid signal molecules which can enable their characterisation with mass spectrometry.
AI platform developed to rapidly identify treatment regimens for infections, including COVID-19
A new AI tool has been created by researchers to identify the best treatment courses and doses for bacterial or viral infections, such as COVID-19.
Synthetic antibodies show efficacy against bunyaviruses, study finds
Having developed synthetic antibodies made of VHH complexes, researchers showed that these could be used to combat bunyaviruses successfully.
Scientists complete genomic study of herpes simplex virus
Researchers have unravelled the viral transcriptome and translatome of the herpes simplex virus (HSV-1) to aid disease research and immunotherapy.
CBD could work as effective glioblastoma treatment, study finds
A study has shown that cannabidiol (CBD) slows cancer cell growth and is toxic to human glioblastoma cell lines, presenting a possible treatment.
Multidrug nanoparticles developed for treatment of COVID-19 inflammation
Multidrug nanoparticles for the targeted delivery of drugs could be used to combat inflammation in COVID-19 patients, say researchers.
NIAID releases strategic plan, outlining COVID-19 research priorities
The US National Institute of Allergy and Infectious Diseases (NIAID) plan outlines four research priorities, including furthering understanding of SARS-CoV-2 viral transmission and pathogenesis and development of animal models.