Study shows structure of biocatalysts changes in certain environments
Researchers have found that the structure of biocatalysts such as enzymes depends on whether they are in cells or in the test tube.
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Novel antibody slows cancer growth and metastasis in mice
The antibody targets a cell receptor in blood vessels and slowed breast and lung cancer growth as well as metastasis in murine models.
Larval protein could suppress inflammatory reactions, say researchers
A study has revealed that a protein of roundworm larvae which needs to invade the intestines of rodents to survive could be used to control inflammation.
Cell types enabling initial COVID-19 infection identified by researchers
An international group of researchers has revealed that goblet and ciliated cells in the nose have high levels of the entry proteins for the SARS-CoV-2 coronavirus.
Hyperferritinaemia could be causing severe COVID-19
Professor Yehuda Shoenfeld suggests hyperferritinaemia, a condition caused by high ferritin levels, may be causing the severe COVID-19 symptoms.
New malaria vaccine candidate shows promise in non-human primates
Using an antibody to a particular malaria protein called PfGARP, researchers have developed a new strategy for designing a malaria vaccine.
Researchers identify drug target to treat cocaine addiction
Researchers have revealed the importance of dopaminergic control on striatal responses to psychostimulants, suggesting a drug target for cocaine addiction.
Research focus should remain on high quality studies during COVID-19 pandemic, say scientists
Exceptions to high quality research should not be made simply because of the COVID-19 pandemic, argue scientists in a new commentary.
UK organisations call for investigation of ethnicity and COVID-19 incidence and outcome
The UK National Institute of Health Research (NIHR) and UK Research and Innovation (UKRI) wish to fund research exploring if people from black, Asian and middle eastern backgrounds are disproportionately at risk from COVID-19.
Induced pluripotent stem cells and CRISPR reversed diabetes in mice
Induced pluripotent stem cells made to produce insulin and CRISPR, used to correct a genetic defect, cured Wolfram syndrome in mice.
Self-aligning smart microscope achieves unprecedented resolution
The developers of the ultra-precise single-molecule microscope demonstrated it can resolve interactions between molecules within living cells and is compatible with existing microscopes.
Researchers identify lead compounds for treatment of telomere diseases
Researchers investigating telomere dieases such as dyskeratosis congenita have found lead compounds that reverse cellular ageing in mouse models of the condition.
Fundamental molecular research underpins our ability to combat COVD-19, says article
Ali Shilatifard’s article explains how investment in institutes performing molecular research is essential, as it is the foundation for all attempts to combat COVID-19 and other future pandemics.
Lead SARS-CoV-2 inhibitor compound identified by researchers to treat COVID-19
Researchers have found a lead compound which they say inhibits SARS-CoV-2 viral replication and demonstrates good pharmacokinetic activity in vivo.
Could T-cell immunotherapy be the answer to COVID-19?
Scientists from Singapore have argued that T-cell immunotherapy can be used to combat a range of infectious diseases, including COVID-19.