UK Consortium to monitor spread and behaviour of coronavirus 24 March 2020 | By Hannah Balfour (Drug Target Review) The UK government has invested £20 million into the COVID-19 Genomics UK Consortium, which will use whole genome sequencing to inform infection control measures and therapeutic developments.
Early natural killer cells more effective than adult versions, find researchers 24 March 2020 | By Victoria Rees (Drug Target Review) Researchers have shown that natural killer (NK) cells work best as an immunotherapy when in an early stage of development, so could be manufactured from pluripotent stem cells.
COVID-19 research hub: promoting scientific collaboration 24 March 2020 | By Drug Target Review Drug Target Review has created a COVID-19 research hub with forum space for discussions and a place to share your research - plus all of our articles and news.
New compound could alleviate side effects of antidepressant drugs 23 March 2020 | By Victoria Rees (Drug Target Review) Researchers have revealed a new substance that can bind well to serotonin transporters, offering a potential way to lessen the side effects of antidepressant therapies.
Researchers to screen compound library for antiviral drugs to combat COVID-19 23 March 2020 | By Victoria Rees (Drug Target Review) Scripps Research has announced it will screen over 14,000 compounds to see if any present significant activity against COVID-19, for use in a therapeutic.
Scientists propose new precise method to measure atoms 23 March 2020 | By Victoria Rees (Drug Target Review) A team of Russian scientists has suggested a new method to measure the sizes of atoms as well as their intermolecular interactions, which they say could help drug design.
High-speed microscope can capture brain signals and calcium concentrations 23 March 2020 | By Hannah Balfour (Drug Target Review) The novel technology allows researchers to create three-dimensional images of signal propagation and calcium concentration changes in the neocortex of live mice.
Study shows how skin cells change when preparing to heal wounds 23 March 2020 | By Hannah Balfour (Drug Target Review) The researchers hope their study into how cellular heterogeneity changes as the skin heals wounds will allow further research into pathological conditions that cause poor wound healing.
Preliminary SARS-CoV-2 protease inhibitor shows efficacy in mice 20 March 2020 | By Victoria Rees (Drug Target Review) Using X-ray crystallography, researchers have revealed the structure of the SARS-CoV-2 main protease, designing an inhibitor to bind to this target and prevent viral replication.
Understanding of COVID-19 infections in children will aid treatment development, say researchers 20 March 2020 | By Victoria Rees (Drug Target Review) A statement from scientists has highlighted that improving the understanding of COVID-19 infections in children will help researchers to develop better treatments.
Novel phage display technique could lead to new peptide-based therapeutics 20 March 2020 | By Hannah Balfour (Drug Target Review) Researchers have shown that incorporating noncanonical amino acids (ncAAs) in phage display expands the range of peptides it can identify.
New cancer treatment regimens could be identified with novel technology 20 March 2020 | By Rachael Harper (Drug Target Review) A new technology called mass cytometry, or CyTOF, is providing new insights into a range of key proteins in blood cancer cells.
Autonomous Scanning Probe Microscopy technique developed using AI 20 March 2020 | By Victoria Rees (Drug Target Review) Using AI and deep learning, researchers have enhanced Scanning Probe Microscopy (SPM) and made their automated resource available for scientists.
Developing a COVID-19 testing kit using RNA detection 20 March 2020 | By Hannah Balfour (Drug Target Review) The developers of an RNA imaging technology are using it to create a COVID-19 coronavirus testing kit, able to recognise the viral genome.
Heparan sulfate could provide new treatment for acetaminophen overdose 19 March 2020 | By Victoria Rees (Drug Target Review) Researchers have demonstrated that in mice, a newly developed heparan sulfate molecule can provide an effective alternative treatment for overdoses of acetaminophen.
