Largest genome sequencing project launched in UK
The UK Biobank, the world’s largest genetics project, will sequence 500,000 genetic samples, which will be available to researchers everywhere.
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Inflammatory regulator molecule identified by study
Researchers have discovered an enzyme that is pivotal in deciding whether cells survive or die in inflammatory diseases, so provides a drug target.
New gene therapy repairs neuron stroke damage in mice
Researchers have developed a new treatment method which turned glial cells into functioning neurons in mice after stroke.
Nervous system discovery overturns previous theory
A ground-breaking nervous system discovery could be significant for the treatment of different neurological diseases.
Schizophrenia gene regulator identified by study
Using both computational models and stem cell-based experiments, researchers have identified a gene regulator of schizophrenia.
CAR T-cell therapy could be harnessed to treat heart disease
New study finds immunotherapy reduces cardiac fibrosis and restores heart function in mice after cardiac injury.
New biological targets could lead to therapies for drug-resistant cancers
A study on how Polycombs regulate cellular identity could lead to alternative treatments for patients with drug-resistant cancer.
Protein vital for breast cancer metastasis discovered
A research team have identified a protein that binds breast cancer cells together, allowing them to metastasise, which could be significant in the development of cancer therapies.
Researchers prevent schizophrenia progression in mice
Using mice models in late adolescence, researchers have successfully treated schizophrenia which could help develop therapies for the condition.
Overcoming resistance in pancreatic cancer treatment
Researchers have developed a new cocktail of drugs that shrink pancreatic tumours in mice by blocking pathways that cancer cells use.
Proteomic approach reveals metastatic melanoma resistance to therapies
A study has used a proteomic method to uncover why some melanoma tumours do not respond to immunotherapy, which could improve treatments.
Researchers identify key mechanism of typhoid toxin
The process of Salmonella typhi to damage DNA has been revealed by researchers at the University of Sheffield which could inform treatments.
Molecule discovered that regulates development of tumours
Researchers discover that a non-coding region of the genome originates a key molecule for the proliferation of cancerous tumours.
HIV infant model opens new avenues for research
An animal model to test HIV infection in infants could lead to biomarkers that predict viral rebound after ART interruption.
Compound promotes healing of myelin in nervous system disorders
A compound that promotes the rebuilding of the protective sheath around nerve cells damaged in multiple sclerosis has been developed.