Dementia spreads via connected brain networks, finds study
New findings on dementia reveal that brain atrophy spreads via connected brain networks, rather than simply adjacent areas of the brain.
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Researchers develop new immuno-oncology technique
A team has used viral gene editing and CRISPR to form a system that marks tumours for destruction, potentially improving immunotherapies.
Cancer-suppressing cells identified in pancreatic cancer
Cells containing Meflin play a role in restraining the progression of pancreatic cancer and could lead to new therapies against the disease.
Microglia critical for neurodegeneration in mice, study finds
Microglia brain immune cells are vital in conjunction with the APOE4 gene during the development of Alzheimer’s in mouse models, researchers have found.
CRISPR RNA-cutting enzyme programmed to kill viruses in human cells
Researchers have developed CRISPR-Cas13 enzyme-based technology that can be programmed to both detect and destroy RNA-based viruses in human cells.
‘Tricking’ bacteria could lead to more effective antibiotics
A technique to 'trick' bacteria into revealing pores in their cell walls has been developed and targeting these could make antibiotics more effective.
3D tissue models of brain tumours created in brain-mimicking environment
A new platform has the potential to better understand what dictates the invasive behaviour of brain tumours.
AI can predict which research will translate to clinical trials
Researchers have created an AI model that analyses the citations of studies, predicting their potential for eventual clinical application.
Bacterial strain identified that determines fate for rotavirus sufferers
Scientists in the US have identified a particular bacterial strain, Segmented filamentous bacteria (SFB), that can prevent and cure rotavirus in mice.
New therapeutic target identified for pulmonary fibrosis
A genetic mutation that causes idiopathic pulmonary fibrosis has been identified and could lead to a new therapeutic approach to treating the disease.
Best targets for immunotherapy identified by new model
A new algorithm has been developed which personalises which cancer mutations are best targets for immunotherapy.
Study reveals potential of gamma delta T cells to combat breast cancer
Researchers have discovered that a specific subset of gamma delta T cells can be found in higher numbers of breast cancer survivor tissue, indicating its role in fighting the condition.
Alzheimer’s disease linked to tau-mediated RNA splicing errors
A new study has shown the possibility of using RNA splicing as a potential molecular target for Alzheimer's disease.
Research reveals calcium signalling pathway in T cells
A study has uncovered the mechanism behind calcium entry and exit into T cells, which could be used in development of autoimmune disease treatments.
Gene therapy for DMD safely preserves muscle function
Gene therapy for the treatment of Duchenne muscular dystrophy has safely stopped the muscle deterioration associated with the disease.